November 26, 2025

How antibody therapy clears Alzheimer’s plaques: Key immune mechanism identified

November 26, 2025 / Clinical Practice / InnovateMed Author / alzheimer

by VIB (the Flanders Institute for Biotechnology) edited by Gaby Clark, reviewed by Robert Egan Editors’ notes This Imaris reconstruction illustrates Lecanemab (pink) taken up by human microglia (light blue) surrounding amyloid plaques (green). This visualization captures the core concept of the study, which is that effective amyloid removal depends on the engagement of microglia (through the Fc […]

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Virtual retina could help unlock new vision loss treatments

November 26, 2025 / Research update / InnovateMed Author / vision loss

by University of Surrey edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain New computer modeling could help scientists better understand how the retina regenerates, opening the door to new treatments for vision loss, according to a study from the University of Surrey. The first-of-its-kind model is capable of detailing how the retina—the

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Scientists develop one-product-fits-all immunotherapy for pancreatic cancer

November 26, 2025 / Research update / InnovateMed Author / pancreatic cancer

by Linda Wang, University of California, Los Angeles edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Microscopy image showing a stem cell-engineered CAR-NKT cell (blue) attacking a human solid tumor cell (magenta). Credit: Lili Yang Lab/UCLA Pancreatic cancer is among the deadliest forms of cancer, with most patients diagnosed after the disease has already spread throughout the

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The cancer blood test making waves, and what the numbers really show

November 26, 2025 / Research update / InnovateMed Author / Blood test

by John Ferguson, The Conversation edited by Lisa Lock, reviewed by Andrew Zinin Editors’ notes Credit: Artem Podrez from Pexels Progress in cutting the global toll of cancer remains painfully slow, but a new blood test has sparked unusual levels of hope. Researchers say it could one day make routine screening far more effective by catching cancers earlier,

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Study reveals unexpected link between dopamine and serotonin in the brain

November 26, 2025 / Research update / InnovateMed Author / dopamine

by Karolinska Institutet edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Illustration depicting a model of how DA and serotonin cotransmission shapes behavior through frequency-dependent filtering of D1-MSN axons. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adx4577 Researchers at Karolinska Institutet, Columbia University and the University of San Francisco, have uncovered a previously unknown mechanism by which dopamine, a key

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Chronic pruritus prevalent among older adults

November 26, 2025 / Clinical Practice / InnovateMed Author / chronic pruritus

by Elana Gotkine edited by Gaby Clark, reviewed by Andrew Zinin Editors’ notes Chronic pruritus is prevalent among older adults and is associated with moderately impaired pruritus-specific quality of life, according to a study published online Nov. 10 in Acta Dermato Venereologica. Juliette F. Bollemeijer, M.D., from Erasmus MC University Medical Center in Rotterdam, Netherlands, and colleagues conducted a cross-sectional

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Alternative sweetener sorbitol linked to liver disease

November 26, 2025 / Research update / InnovateMed Author / liver disease

by Leah Shaffer, Washington University in St. Louis edited by Lisa Lock, reviewed by Robert Egan Editors’ notes Credit: Pixabay/CC0 Public Domain Sweeteners such as aspartame, found in Equal packets, sucralose (Splenda), or sugar alcohols are often seen as healthier alternatives to food with refined sugar (glucose). But that assumption is being challenged with new research, including the

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Many men may not need long-term hormone therapy for prostate cancer, study suggests

November 26, 2025 / Research update / InnovateMed Author / prostate cancer

by Denise Heady, University of California, Los Angeles edited by Lisa Lock, reviewed by Robert Egan Editors’ notes Credit: Alex Green from Pexels A study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that most of the benefits of androgen deprivation therapy (ADT) for prostate cancer occur within the first 9 to 12 months.

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Tattoos could be a risk factor for melanoma

November 26, 2025 / Research update / InnovateMed Author / melanoma

by Åsa Hansdotter, Lund University edited by Lisa Lock, reviewed by Robert Egan Editors’ notes Credit: cottonbro studio from Pexels An increasing number of Swedes are getting tattoos and Sweden’s population is now one of the most tattooed in Europe. At the same time, the incidence of melanoma is increasing. A new epidemiological study from Lund University in

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Newly identified immune cell type could hold key to preventing scar tissue buildup in wounds

November 26, 2025 / Research update / InnovateMed Author / scar tissue

by Emma Dickey and Steve Benowitz, University of Arizona edited by Robert Egan Editors’ notes Human confirmation of mechanoresponsive signal pathways. Credit: Nature Biomedical Engineering (2025). DOI: 10.1038/s41551-025-01479-5 Researchers at the University of Arizona have uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead

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