pancreatic cancer

by Perelman School of Medicine at the University of Pennsylvania edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Effects of RAS(ON) inhibition on the pre-TME after 3 doses. Credit: Science (2026). DOI: 10.1126/science.aec7929 A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have […]

by Candace Gwaltney, Indiana University edited by Robert Egan  Editors’ notes  The GIST Add as preferred source Melissa Fishel’s lab found that depleting a clotting protein made by the liver could slow down pancreatic cancer. Credit: Tim Yates, IU School of Medicine Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that

by National Taiwan University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source The PanMETAI platform integrates AI with NMR metabolomics to detect pancreatic cancer from a small blood sample, offering a rapid and non-invasive diagnostic tool validated across international cohorts. Credit: Nature Communications A team of researchers from Taiwan has developed

by Angela Yeager, Oregon Health & Science University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Oregon Health & Science University researchers have found that certain nerves that play an integral role in the body’s “fight or flight” stress response can support pancreatic tumor growth. These

by Duke-NUS Medical School edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Zhong et al. report the critical role of oncogenic KRAS/ERK/JUNB signalling in suppressing GATA6, the master regulator of differentiation in pancreatic cancers. Key proteins in pancreatic cancer xenografts were detected by immunohistochemical staining, with the resulting photomicrographs enhanced

by Miles Martin, University of California – San Diego  Editors’ notes  The GIST Add as preferred source A test tumor from a CMV-infected mouse, treated with CMV peptides. Pink represents cell death. Credit: UC San Diego Health Sciences Researchers at the University of California San Diego have discovered a promising new treatment approach for pancreatic cancer,

by Cold Spring Harbor Laboratory edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Stress signals redesign tissues during inflammation and cancer. Left: Normal tissue maintenance. Right: Stress signals “switch on” fibroblasts, turning them into myCAFs (purple) that actively recruit nerves (cyan) into the pancreas. Credit: Tuveson lab/CSHL Notoriously tricky to

by American Association for Cancer Research edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain A four-biomarker blood panel of aminopeptidase N (ANPEP), polymeric immunoglobulin receptor (PIGR), CA19-9, and thrombospondin-2 (THBS2) enhanced the detection of pancreatic ductal adenocarcinoma (PDAC) compared to measuring CA19-9 levels alone, according to