stem cell therapy

Stem cell expert Q&A: Innovative pathways in biomedical research

by Cedars-Sinai Medical Center edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Clive Svendsen, Ph.D., with an organ-chip that replicates conditions cells would experience in an actual organ and is one of several new research methodologies. Credit: Cedars-Sinai Medical Center New scientific methods could one day render animal studies—the standard […]

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How stem cell therapy can regenerate brain tissue after a stroke

by Daniel Tornero Prieto, Alba Ortega Gascó, Santiago Ramos Bartolomé, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes Image of neural cultures derived from stem cells growing in a microfluidic device with two compartments connected by microchannels (400 μm). Overexpression of BDNF in the lower compartment promotes the growth and projection of axons from

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Stem cell-derived dopamine neurons improve depression-like behaviors in mice

by Justin Jackson, Phys.org edited by Sadie Harley, reviewed by Robert Egan   Graphical abstract. Credit: Cell Stem Cell (2025). DOI: 10.1016/j.stem.2025.07.007 The Institute of Neuroscience, Chinese Academy of Sciences, reports that human stem cell-derived A10-like midbrain dopaminergic neurons integrate into mouse mesocorticolimbic circuits and suppress anxiety and depression behaviors upon activation. Midbrain dopaminergic neurons regulate voluntary movement, reward, motivation, cognition, and

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Japan firm seeks approval for stem cell treatment for Parkinson’s

The Gist, edited by Andrew Zinin Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Japanese drugmaker Sumitomo Pharma said Tuesday it is seeking approval for a Parkinson’s disease treatment that transplants stem cells into a patient’s brain, following a successful clinical trial. The

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