October 2025

Blocking a key protein can double yield and increase potency of muscle-regenerating cells

by Sanford-Burnham Prebys edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Human muscle cells derived from the Caputo et al. optimized protocol efficiently regenerate muscle tissue upon transplantation in mice. Credit: Lale Cecchini, Sacco lab, Sanford Burnham Prebys If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body’s […]

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Study shows vaccine protection against Salmonella Paratyphi A infection

by University of Oxford edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: CC0 Public Domain An Oxford-led study has demonstrated that an oral live-attenuated vaccine, CVD 1902, provided significant protection against S. Paratyphi A infection in healthy adults using a controlled human infection model, without any safety concerns. The research is published in the New England Journal of

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Experimental cancer drug shows exceptional tumor-fighting potential

by Medical University of Vienna edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes LiPyDau treatment inhibits the growth of a patient-derived lung adenocarcinoma xenograft. Credit: Molecular Cancer (2025). DOI: 10.1186/s12943-025-02444-1 A research team has developed a new chemotherapeutic agent, LiPyDau, which shows remarkable efficacy against multiple tumor types in preclinical studies. Published in the journal Molecular Cancer, the study introduces a

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Connection between liver and brain in the context of metabolic liver disease revealed

by University of Seville edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Behavior, neurocognitive aspects, and sensorimotor processing/gating in a nonobese preclinical animal model of diet-induced MASLD. Credit: Science Advances (2025). DOI: 10.1126/sciadv.ady9758 A multidisciplinary research team has discovered that liver alterations associated with metabolic dysfunction–associated fatty liver disease (MASLD) can directly cause cognitive and neurological impairments, and

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Previously unrecognized hub in the brain’s lymphatic drainage system may assist with clearing waste

by George Hanna, Medical University of South Carolina edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Microscope image showing lymphatic vessels (red) in the brain’s outer protective layer, called the dura. These vessels form a rich and complex network that helps drain waste from the brain. Credit: Dr. Onder Albayram How does the brain take out

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Genetic mechanisms reveal how toxic substances damage balance cells in the inner ear

by University of Barcelona edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Decreased expression of three proteins in the vestibular epithelium following treatment with streptomycin. Credit: Journal of Biomedical Science (2025). DOI: 10.1186/s12929-025-01180-4 The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer

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FDA approves Blenrep for relapsed or refractory multiple myeloma

by Lori Solomon edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes The U.S. Food and Drug Administration approved Blenrep (belantamab mafodotin-blmf) in combination with bortezomib and dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma. The approval is for patients who have received at least two prior lines of therapy, including

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Research reveals how talking, age and hydration affect airborne disease spread

by Clarkson University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: Clarkson University A new study from Clarkson University is uncovering surprising clues about how simple, everyday actions—like talking or singing—may influence how diseases spread through the air in indoor environments. Ph.D. candidate Mahender Singh Rawat, working with Professor Andrea Ferro’s research team in Clarkson’s

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Maxing out your fiber intake can have broad health benefits

by Emily Brognano, Tufts University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain The amount of fiber you consume can have significant impacts on your body. From healthy digestion, to reducing your risk of developing cancer, eating fiber has huge benefits—which may be why the fibermaxxing trend is taking over. Fibermaxxing—or the

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Predicting the risk of heart disease and dementia in older adults: Q&A

by Yale University edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: CC0 Public Domain More than 70% of people over 70 years old will one day develop cardiovascular disease, highlighting the need for effective diagnosis, treatment, and care for this population. “When you ask older people with cardiovascular disease what their top health priority is, they will

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