November 26, 2025

Long-term calorie restriction may slow normal brain aging

by Boston University School of Medicine edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes CR synaptic OL subcluster is enriched for essential myelin synthesis pathways. Credit: Aging Cell (2025). DOI: 10.1111/acel.70298 As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage. These cellular issues impair the ability to maintain the myelin […]

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Pro fighters risk damage to the brain’s ‘garbage disposal’

by Radiological Society of North America edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes The brain’s waste-clearing system significantly declines in function with repeated head impacts, according to a new study of cognitively impaired professional boxers and mixed martial arts fighters. Color display of diffusion tensor imaging indicating the distribution of projection fibers (z-axis: blue), association

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Is AI making some people delusional? Families and experts are worried

by Nilesh Christopher edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain Generative artificial intelligence has quickly permeated much of what we do online, proving helpful for many. But for a small minority of the hundreds of millions of people who use it daily, AI may be too supportive, mental health experts

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Why certain arthritis drugs don’t work in rheumatoid arthritis

by Cedars-Sinai Medical Center edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Towfiqu barbhuiya from Pexels Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don’t work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes that occur in immune cells within the joints as the

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Finerenone shows superior survival and kidney protection over spironolactone in diabetic kidney disease

by National Taiwan University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Comparative outcomes of finerenone versus spironolactone in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D). Credit: National Taiwan University Researchers from National Taiwan University Hospital and collaborating institutions have demonstrated that finerenone, a new-generation nonsteroidal mineralocorticoid receptor antagonist (MRA), significantly reduces

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Should You Add a Ginger Shot to Your Drinks? A Review of the Benefits Before You Decide

Key takeaways: Ginger is full of anti-inflammatory compounds that can help with digestion, nausea, and pain relief. Drinking ginger shots might help lower blood sugar and reduce the risk for diabetes. A ginger shot isn’t the only way to get the benefits of ginger, but it gives you the most concentrated, whole-food form. Ginger shots

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FDA approves Otsuka’s kidney drug, paving the way for novel mechanism

The FDA yesterday approved a novel drug from Otsuka to treat a chronic, autoimmune kidney disease. The drug, called Voyxact, is part of an emerging class of drugs for IgA nephropathy, or IgAN, a disease caused by the build-up of immune antibodies in the kidneys. The condition, which leads to progressive loss of kidney function, can

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Reducing social media use for just a week can improve mental health

by Krystal Kasal, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain In a new study, published in JAMA Network Open, 295 participants report promising mental health benefits after reducing their social media usage for a week. The cohort consisted of young adults from the ages of 18 to 24—the age group commonly associated

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An fMRI marker of Alzheimer’s-related cognitive decline

by Justin Jackson, Medical Xpress edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Sagittal and coronal views of the components number 2 and 10 obtained by group ICA, the default mode network (DMN) and dorsal attention network (DAN) respectively. Credit: NeuroImage (2025). DOI: 10.1016/j.neuroimage.2025.121509 Researchers at Université Savoie Mont Blanc, Radboud University and the University of Oxford’s Wellcome

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Drug Used for Enlarged Prostate Tied to High Glaucoma Risk

Edited by Archita Rai November 17, 2025   TOPLINE: Men with benign prostatic hyperplasia (BPH) who took alpha-blockers to manage the condition were roughly 50% more likely to develop acute angle-closure glaucoma than were those who did not use the medication, and the incidence increased with longer exposure to the drugs. METHODOLOGY: Researchers investigated whether

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