Pain Management

New on-switch for pain signaling pathway could lead to safer treatment and relief

by Tulane University edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Public Domain Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead to safer, more effective treatments. The study, co-led by Matthew Dalva, director […]

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Mouse study links chronic pain to disrupted sleep patterns

by Kelsey Arends, Washington University in St. Louis edited by Gaby Clark, reviewed by Andrew Zinin   Indicators of the inflammatory effect of CFA compared to baseline, 24 h after saline injection, and 24 h, 1 week, 2 weeks, and 3 weeks after CFA injection. Credit: Neuropsychopharmacology (2025). DOI: 10.1038/s41386-025-02152-w Pain and sleep disturbances often go hand in hand—more than 30% of

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