October 22, 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

October 22, 2025 / Research update / InnovateMed Author / blood brain barrier

By Hugo Francisco de SouzaReviewed by Susha Cheriyedath, M.Sc.Oct 21 2025 By decoding the blood-brain barrier’s intricate structure and function, researchers are paving the way for new therapies that can safely breach the brain’s toughest defense. Primer: The blood–brain barrier. Image Credit: Love Employee / Shutterstock In a recent primer paper published in the journal Current Biology, researchers elucidated […]

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Rethinking how bone marrow works

October 22, 2025 / Research update / InnovateMed Author / bone marrow

Scientists at Cincinnati Children’s provide fresh guidance in a global quest to decode the mechanics of blood cell formation. At stake? Better answers to some of the most elusive questions in cancer research Peer-Reviewed Publication Cincinnati Children’s Hospital Medical Center image: Logo for Cincinnati Children’s view more Credit: Cincinnati Children’s One huge reason why the world

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Tears could open a new avenue for diagnosing and monitoring eye and neurodegenerative diseases

October 22, 2025 / Research update / InnovateMed Author / neurodegenerative disease

Peer-Reviewed Publication Germans Trias i Pujol Research Institute image: IVECAT Group at IGTP view more Credit: IGTP Researchers from the Germans Trias i Pujol Research Institute and Hospital have reviewed the current knowledge on the use of tear-derived extracellular vesicles as a source of biomarkers for both ocular and neurodegenerative diseases. In their work, published in Extracellular

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New compound cuts off protein supply to parasites

October 22, 2025 / Research update / InnovateMed Author / parasite

Researchers develop new drug candidate for treating resistant malaria pathogens Peer-Reviewed Publication Helmholtz Centre for Infection Research Today, more than 260 million people are infected each year with the parasite Plasmodium falciparum – the pathogen that causes malaria. In Germany, the annual number of cases is currently still in the three-digit range. However, experts expect these numbers

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U Iowa study links multiple sclerosis with distinct oral microbiome

October 22, 2025 / Research update / InnovateMed Author / multiple sclerosis

Comprehensive genetic and metabolic profile from saliva may help diagnose, treat MS Peer-Reviewed Publication University of Iowa Health Care image: Ashutosh Mangalam, PhD, UI professor of pathology, led a study showing that people with multiple sclerosis have a distinct, dysbiotic oral microbiome. The differences may help doctors develop new ways to diagnose, monitor and even

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Adverse pregnancy outcomes and long-term risk of atrial fibrillation

October 22, 2025 / Research update / InnovateMed Author / atrial fibrillation

JAMA Cardiology Peer-Reviewed Publication JAMA Network About The Study: In this large national cohort, all adverse pregnancy outcomes except small for gestational age were associated with increased risk for atrial fibrillation up to 46 years later. Women with adverse pregnancy outcomes need early preventive actions and long-term clinical follow-up for timely detection and treatment of cardiovascular disorders related

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Scientists pinpoint a key gene behind heart defects in Down syndrome

October 22, 2025 / Research update / InnovateMed Author / down syndrome

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. Peer-Reviewed Publication Gladstone Institutes image: After decades of mystery, researchers at Gladstone Institutes identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. view more Credit:

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Stroke can happen to anyone. An expert explains how to spot the signs and act fast

October 22, 2025 / Patient education / InnovateMed Author / Stroke

by Siobhan Mclernon, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin Editors’ notes Credit: CC0 Public Domain Stroke can happen to anyone, at any age and at any time. The number of strokes among younger adults under 55 is rising worldwide, and every day in the UK around 240 people experience the traumatic and life-changing effects

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Bubble tea’s dark side: From lead contamination to kidney stones

October 22, 2025 / Patient education / InnovateMed Author / kidney stones

by Adam Taylor, The Conversation edited by Lisa Lock, reviewed by Andrew Zinin Editors’ notes Credit: Pixabay/CC0 Public Domain They’ve become as ubiquitous on British high streets as coffee shops—bubble tea outlets offering their Instagram-worthy drinks in countless flavor combinations. The Taiwanese beverage, a blend of black tea, milk, sugar and chewy tapioca pearls, has gained global popularity

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Stiff arteries may amplify early memory decline in older adults

October 22, 2025 / Research update / InnovateMed Author / stiff artery

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research edited by Gaby Clark, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain Findings from the multisite IGNITE clinical trial suggest that arterial stiffness, which occurs when large blood vessels lose their natural flexibility, may be linked to greater injury effects to brain nerve fibers

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