October 22, 2025

Breast cancer protein discovery could restore hormone therapy response

October 22, 2025 / Research update / InnovateMed Author / breast cancer protein

by Cold Spring Harbor Laboratory edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes A mammary tumor from a BPTF knockout mouse; animals with lower levels of this protein had fewer cancer metastases and lived longer than those with normal BPTF levels. Credit: dos Santos lab / CSHL Know someone who’s been diagnosed with breast cancer? There’s […]

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Researchers find a new targeted approach to shut down prostate cancer growth

October 22, 2025 / Research update / InnovateMed Author / prostate cancer

by Anna Megdell, University of Michigan edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes p300/CBP-catalyzed H2BNTac is significantly elevated in prostate cancer lesions compared with normal prostate epithelia. a, Representative multiplex immunofluorescence images of H2BK5ac/KRT8 (green and gray) and H2BK20ac/KRT8 (cyan and gray) staining in patient-matched adjacent benign and tumor tissues. Magnification, ×200. b. H2BK5ac and H2BK20ac IF

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Q&A: Putting weighted vests to the test—here’s what research shows

October 22, 2025 / Research update / InnovateMed Author / weighted vest

by Alicia Roberts, Wake Forest University edited by Lisa Lock, reviewed by Robert Egan Editors’ notes Credit: SHVETS production from Pexels Nearly a decade ago, Kristen Beavers, who studies safe ways for older adults to lose weight, began asking whether weighted vests could help this population drop pounds without sacrificing vital bone mass and lean muscle. Now, in

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It’s not just diet: Where a child lives can also raise type 2 diabetes risk

October 22, 2025 / Research update / InnovateMed Author / type 2 diabetes risk

by Florida Atlantic University edited by Gaby Clark, reviewed by Robert Egan Editors’ notes Findings reveal strong links between risk and environmental factors like walkability, litter, and access to processed foods. Children in food-insecure homes or areas with limited green space showed higher risk indicators. Credit: Alex Dolce, Florida Atlantic University Type 2 diabetes (T2D), once considered an

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Antidepressants vary widely in their physical side effects, highlighting the need for personalized prescribing

October 22, 2025 / Clinical Practice / InnovateMed Author / antidepressants

by Lancet edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain Antidepressants can differ widely in how they physically affect the body, including around a 4 kg difference in weight change between certain drugs (approximately 2.5 kg weight loss from agomelatine and 2 kg weight gain from maprotiline), confirms a systematic review and

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Acoustic neuromodulation, customized to each person’s brainwave patterns, may improve well-being

October 22, 2025 / Clinical Practice / InnovateMed Author / acoustic neuromodulation

by Myra Wright, Wake Forest University School of Medicine edited by Gaby Clark, reviewed by Robert Egan Editors’ notes Since 2011, the Brain Body Research Program at Wake Forest University School of Medicine has evaluated a closed-loop, acoustic neuromodulation technology (Cereset Research), that translates brainwaves into personalized tones in near real time. The echoed tones engage the

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Number of steps taken matters more for better health in older women than the frequency, study suggests

October 22, 2025 / Research update / InnovateMed Author / better health

by British Medical Journal edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain Clocking up at least 4,000 daily steps on just one or two days per week is linked to a lower risk of death and cardiovascular disease among older women, finds research published online in the British Journal of Sports Medicine. This

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Scientists develop a way to track donor bacteria after fecal microbiota transplants

October 22, 2025 / Research update / InnovateMed Author / fecal microbiota transplant

by The Mount Sinai Hospital edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain Researchers at the Icahn School of Medicine at Mount Sinai and their collaborators have developed a new technology to track beneficial bacteria after fecal microbiota transplants (FMT). The approach provides a detailed view of how donor microbes take hold

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Stopping long-term opioid treatment unlikely to increase suicide risk, major study finds

October 22, 2025 / Clinical Practice / InnovateMed Author / suicide risk

by University of New South Wales edited by Sadie Harley, reviewed by Alexander Pol Editors’ notes Credit: CC0 Public Domain People on long-term opioid treatment can be reassured that stopping these medicines is not likely to increase their risk of suicide or fatal overdose, thanks to a major new study from the National Drug and Alcohol Research Center

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When we dream, does our brain wake up?

October 22, 2025 / Research update / InnovateMed Author / brain wakeup

by Bial Foundation edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Ron Lach from Pexels An international consortium of researchers has created the largest-ever database compiling records of brain activity during sleep and dream reports. One of the first analyses of the database confirmed that dreams do not occur only during REM sleep, but

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