neurodegenerative disease

A new molecular atlas of tau enables precision diagnostics and drug targeting across neurodegenerative diseases

by Children’s Hospital Boston edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Graphical abstract. Credit: Cell (2026). DOI: 10.1016/j.cell.2025.12.036 Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as “tauopathies”). New research led by Boston Children’s Hospital challenges the current “one-size-fits-all” approach to diagnosing and treating these tauopathies. […]

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HKUST co-develops robotic nanoprobe for precise mitochondria extraction charting new directions in research on therapies for neurodegenerative diseases and cancer

Peer-Reviewed Publication Hong Kong University of Science and Technology image: A team led by Prof. Richard GU Hongri, Assistant Professor in the Division of Integrative Systems and Design of the Academy of Interdisciplinary Studies at HKUST, in collaboration with experts in mechanical engineering and biomedicine, has developed an innovative automated nanoprobe capable of precisely extracting

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Microglia replacement paves way for neurodegenerative disease therapies, moving from mice to humans in just 5 years

December 4, 2025  The GIST by Fudan University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes In the microglia fully tiled brain, the proliferation and migration of microglia are inhibited by their neighboring cells. When the neighboring microglia are removed, the lateral inhibition is released, enabling microglial proliferation and migration towards the microglia-free region. The source

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Tears could open a new avenue for diagnosing and monitoring eye and neurodegenerative diseases

Peer-Reviewed Publication Germans Trias i Pujol Research Institute image: IVECAT Group at IGTP view more   Credit: IGTP Researchers from the Germans Trias i Pujol Research Institute and Hospital have reviewed the current knowledge on the use of tear-derived extracellular vesicles as a source of biomarkers for both ocular and neurodegenerative diseases. In their work, published in Extracellular

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Research gives insight into effect of neurodegenerative diseases on speech rhythm

by University of Kansas edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Panying Rong shows some of the equipment researchers in her lab use to measure speech organs. Credit: Rick Hellman / KU Speech rhythm, a key attribute of natural languages that directly influences the effectiveness and efficiency of communication, is often compromised in people with

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Neurodegenerative diseases: What if the key lies in the mitochondria?

Peer-Reviewed Publication INSERM (Institut national de la santé et de la recherche médicale) Mitochondria, the tiny organelles without which our bodies would be deprived of energy, are gradually revealing their mysteries. In a new study published in Nature Neuroscience, researchers from Inserm and the University of Bordeaux at the NeuroCentre Magendie, in collaboration with researchers from the

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Blood plasma reveals shared pathways in neurodegenerative diseases

by Washington University in St. Louis edited by Lisa Lock, reviewed by Andrew Zinin A framework for mapping human plasma proteome in neurodegeneration. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-025-03833-1 Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer’s disease, Parkinson’s disease and frontotemporal dementia (FTD), and that these proteins

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Key brain protein may hold answers for memory loss and neurodegenerative diseases

by Rutgers University edited by Sadie Harley, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for learning and memory. Results of the study, published in the journal Science Advances, could point the way to new treatments for traumatic brain injuries and diseases, such

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Predictive AI model could help forecast neurodegenerative diseases

Posted Today Neurodegenerative diseases like Alzheimer’s are a growing concern in the U.S., with over 7 million Americans living with Alzheimer’s disease today.  By 2060, that number is expected to grow, affecting nearly 13 million people. These diseases are not only hard on individuals and families, but are costly, with more than $230 billion spent in the

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