multiple sclerosis

Parthanatos pathway behind neuron loss in multiple sclerosis identified

by Ingrid Fadelli, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Diagram of a full section from the lumbar spinal cord of an EAE mouse. The purple are neurons, the white is DNA damage, the arrows are DNA-damaged neurons. Purpose: to show that EAE causes DNA damage in […]

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Study finds shared genetic roots of multiple sclerosis across diverse ancestries

by Queen Mary, University of London edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain A new study published in Neurology, led by Queen Mary University of London, has revealed that people of South Asian, African and European ancestry share many of the same genetic risk factors for multiple sclerosis

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New diagnostic markers for multiple sclerosis discovered in cerebrospinal fluid

by Christiane Menzfeld, Max Planck Society edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Next to brain imaging, laboratory analysis of cerebrospinal fluid is needed for the diagnosis of multiple sclerosis. Credit: TUM, adapted by MPIB Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered

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Cerebral-spinal fluid molecular test improves early and accurate diagnosis of multiple sclerosis

by Chris Casey, CU Anschutz Medical Campus edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Annals of Neurology (2025). DOI: 10.1002/ana.78047 Cerebrospinal fluid (CSF)-based molecular tests can reliably distinguish multiple sclerosis (MS) from other neurological conditions, according to a new study that analyzed cryopreserved CSF samples from 160 individuals. The study

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What if multiple sclerosis isn’t just one disease?

By Chelsea Haney February 04, 2026 Facebook Twitter LinkedIn Reddit Flipboard Email The findings indicate MS could have two distinct degenerative pathways, one fast and the other slow. And this knowledge could help better inform patients and doctors. Depositphotos View 1 Images For decades, multiple sclerosis (MS) has been defined primarily by its symptoms, rather than

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Immune cells linked to Epstein-Barr virus may play a role in multiple sclerosis

by University of California, San Francisco edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source This electron microscopic image of two Epstein Barr Virus virions (viral particles) shows round capsids—protein-encased genetic material—loosely surrounded by the membrane envelope. Credit: PloS Biology (2005), DOI: 10.1371/journal.pbio.0030430.g001 Researchers at UC San Francisco have uncovered a new clue

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Backward walking study results may help to improve mobility and decrease falls in multiple sclerosis patients

by Julie O’Connor, Wayne State University edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain A collaborative team of researchers and students from Wayne State University’s Eugene Applebaum College of Pharmacy and Health Sciences, School of Medicine, College of Liberal Arts and Sciences and Institute of Gerontology

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When a virus releases the immune brake: New evidence on the onset of multiple sclerosis

by University of Basel edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Antigen surveillance by B cells. Credit: Cell (2026). DOI: 10.1016/j.cell.2025.12.031 Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself. Yet for most of them, it remains unclear why this process begins. Researchers have

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Immune response to Epstein-Barr virus linked to brain damage in multiple sclerosis

by Karolinska Institutet edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source This electron microscopic image of two Epstein Barr Virus virions (viral particles) shows round capsids—protein-encased genetic material—loosely surrounded by the membrane envelope. Credit: PloS Biology (2005), DOI: 10.1371/journal.pbio.0030430.g001 The immune system’s reaction to the common Epstein-Barr virus can ultimately damage the

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New insight into the immune signals driving inflammation in multiple sclerosis

by Ingrid Fadelli, Medical Xpress edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Representative confocal microscopy image of a cross-section of the whole spinal column of an EAE animal co-transferred with control (red) and Tgfbr1-KO (green) cells. Credit: de la Rosa, Kendirli et al. Multiple sclerosis (MS) is a chronic

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