inflammation

In football players with repeated head impacts, inflammation related to brain changes and worse memory

by American Academy of Neurology edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain In former college and professional football players, a new study has found higher levels of inflammation were associated with worse brain structure, which in turn was related to worse memory. The study, published […]

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Honeysuckle compounds target key inflammatory signaling pathways

Compuscript LtdFeb 13 2026 Announcing a new publication for Acta Materia Medica journal. Inflammation is a complex biological response essential for tissue repair in acute settings, yet chronic dysregulation contributes to progressive tissue damage and the pathogenesis of numerous diseases. Lonicera japonica Thunb. (honeysuckle), a traditional Chinese medicinal herb renowned for its “heat clearing and detoxifying” properties, exhibits

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Inflammation gives mutated blood stem cells an edge in cancer development

by Olivia Dimmer, Northwestern University edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Graphical abstract. Credit: Journal of Clinical Investigation (2025). DOI: 10.1172/jci184285 A Northwestern Medicine-led study published in the Journal of Clinical Investigation has uncovered why older individuals with specific genetic mutations face a heightened risk of developing serious blood cancers. Clonal hematopoiesis (CH) is

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Scientists Discover the Body’s Natural “Off Switch” for Inflammation

By University College LondonJanuary 19, 202611 Comments5 Mins Read Researchers have identified a previously underappreciated biological pathway that helps the human immune system bring inflammation to a close. Credit: Shutterstock A human study reveals how naturally occurring fat-derived molecules help switch off inflammation. Researchers at University College London (UCL) have identified an important biological process that helps the

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Scientists discover natural ‘brake’ that could stop harmful inflammation

by University College London edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Researchers at University College London (UCL) have uncovered a key mechanism that helps the body switch off inflammation—a breakthrough that could lead to new treatments for chronic diseases affecting millions worldwide. Inflammation is the

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AI-designed protein shows 50% greater anti-inflammatory effect in animal studies

by Daegu Gyeongbuk Institute of Science and Technology edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes Credit: Theranostics (2026). DOI: 10.7150/thno.120259 A research team has developed a next-generation anti-inflammatory protein using AI and supercomputing. The team, led by Professor Jiwon Um of the Department of Brain Sciences at DGIST and CEO Iksoo Chang of iProtein Therapeutics, a former

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Persistent inflammation in older adults tied to GDF3 protein signaling

by Alex Smith, University of Minnesota Medical School edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes Gdf3 promotes SMAD-regulated genes via altered chromatin accessibility in ATMs. Credit: Nature Aging (2025). DOI: 10.1038/s43587-025-01034-6 As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis. New research from University of

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CAN FIGHTING INFLAMMATION TREAT DEPRESSION?

DECEMBER 14TH, 2025POSTED BY U. MICHIGAN (Credit: Getty Images) SHARE THIS  ARTICLE Facebook   Twitter   Reddit   Email You are free to share this article under the Attribution 4.0 International license. TAGS DEPRESSION INFLAMMATION UNIVERSITY UNIVERSITY OF MICHIGAN Targeting inflammation may offer hope for depression treatment, researchers report. Depression has been traditionally treated globally as a

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Reducing inflammation may protect against early age-related macular degeneration-like vision loss

by Alex Smith, University of Minnesota Medical School edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes No gross structural changes in the retina or RPE are observed in WT vs. R345W+/+ mice even at ≥20 months of age. Credit: Cell Death & Disease (2025). DOI: 10.1038/s41419-025-08104-y University of Minnesota Medical School researchers have shown that reducing chronic inflammation can

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Mitochondria and lysosomes reprogram immune cells that dampen inflammation

by St. Jude Children’s Research Hospital edited by Alexander Pol   Credit: Pixabay/CC0 Public Domain Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children’s Research Hospital scientists recently uncovered how mitochondria, the powerhouse of cells, and lysosomes, cellular recycling systems, work together

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