depression

No evidence to suggest medicinal cannabis is effective for depression, anxiety or PTSD, says systematic review

by University of Sydney edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain A landmark paper published in Lancet Psychiatry—the largest-ever review of the safety and efficacy of cannabinoids across a range of mental health conditions—found no evidence that medicinal cannabis is effective in treating anxiety, depression or […]

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Free 10‑minute online programs aimed at overcoming depression led to real improvements: New research

by Benjamin Kaveladze, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain A well-designed 10-minute online exercise can spark small reductions in depression. That’s the key finding of my team’s paper, published in Nature Human Behaviour. Many people believe that to start overcoming depression, they need a therapist,

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Single dose of a psychedelic drug can rapidly reduce depressive symptoms, clinical trial suggests

by Nature Publishing Group edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Gerd Altmann from Pixabay A single dose of the psychedelic drug dimethyltryptamine (DMT), given with psychological support, rapidly reduced depressive symptoms in 34 adults with major depressive disorder, according to a clinical trial published in Nature Medicine. The improvements, which

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Single DMT dose treats stress-induced depression more effectively than Prozac in mice

by Ingrid Fadelli, Medical Xpress  Editors’ notes  The GIST Add as preferred source Leão and Lima da Cruz performing a DMT purification procedure. Credit: Lima da Cruz et al. Psychedelics are psychoactive substances that trigger unusual mental states, also referred to as “trips,” altering the perceptions, thoughts, and emotions of those taking them and typically inducing

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Emphasizing the strengths of people with depression can help those affected

by University of Vienna edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source The depression-reframing approach: Reframing the implications of depression experiences. Credit: Personality and Social Psychology Bulletin (2026). https://doi.org/10.1177/01461672251412492 People suffering from depression demonstrate strength in dealing with their illness on a daily basis, but this is often not perceived as such.

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Magnetic pulses to the brain emerge as low-cost lifeline for depression

by University of Nottingham edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain A major new study has found that transcranial magnetic stimulation (TMS), which applies magnetic energy to the brain, can be a cost-effective treatment option for the NHS in treating moderate and severe forms of

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Link between smoking and depression confirmed in study

by Friederike Fellenberg, German National Cohort edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain A research group led by the Central Institute of Mental Health (CIMH) in Mannheim has confirmed for the first time within the German National Cohort (NAKO) an association between cigarette consumption and

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Psilocybin could treat depression via a non-hallucinogenic receptor

by Ingrid Fadelli, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Illustration inspired by the topic of the paper. Credit: Angela Shang. Psychedelics, psychoactive substances that alter people’s perceptions, mood and thought patterns, have recently shown promise for the treatment of some mental health disorders, including depression and

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Implant provides lasting relief for treatment-resistant depression, study finds

by Shawn Ballard, Washington University in St. Louis edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Sara Moser / Washu Medicine About 20% of U.S. adults experience major depression in their lifetime. For most people, symptoms improve within a few treatment attempts, but up to one‐third of patients have

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Depression may be an early warning sign of Parkinson’s disease and Lewy body dementia

Peer-Reviewed Publication Shanghai Jiao Tong University Journal Center image: Hazard rate of incident depression preceding and following diagnosis of Parkinson’s disease, Lewy body dementia, rheumatoid arthritis, chronic kidney disease and osteoporosis. ‘0’ represents the date of diagnosis of Parkinson’s disease, Lewy body dementia, rheumatoid arthritis, chronic kidney disease and osteoporosis. view more  Credit: Christopher Rohde, Martin Langeskov-Christensen, Lene

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