depression

Drinking soft drinks may fuel depression by altering gut bacteria

By Dr. Liji Thomas, MDReviewed by Lauren HardakerOct 10 2025 Researchers have uncovered a surprising link between everyday soft drink habits and mental health, revealing that even moderate soda consumption could alter gut microbes in ways that heighten depression risk, especially among women. Study: Soft Drink Consumption and Depression Mediated by Gut Microbiome Alterations. Image credit: Kmpzzz/Shutterstock.com Consumption […]

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Tiny sugars in the brain disrupt emotional circuits, fueling depression

by Institute for Basic Science edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes A mouse model displaying depression-like behaviors was established by exposing animals to chronic variable stress (left). A multi-omics approach was then applied, using high-resolution mass spectrometry to analyze O-glycan composition and protein alterations across nine distinct brain regions (center). This analysis revealed a

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New precise, personalized brain stim therapy rapidly treats depression

By Paul McClure September 16, 2025   A newer, more precise method of brain stimulation reduces depression severity quickly Depositphotos original extended using Firefly View 2 Images A new study shows that a personalized, precise form of brain stimulation, HD-tDCS, can rapidly ease depression symptoms – and even reduce anxiety – offering a promising drug-free alternative with

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Links between diabetes and depression are similar across Europe, study of over-50s in 18 countries finds

by European Association for the Study of Diabetes edited by Sadie Harley, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain The relative increase in odds of an individual with diabetes developing severe symptoms of depression—and vice versa—is the same, regardless of where they live, a study of over-50s in 18 countries in Europe presented at the Annual

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Depression linked to specific altered brain cells—findings open door to new treatments

by Keila DePape, McGill University edited by Gaby Clark, reviewed by Robert Egan   Chromatin architecture at the single-cell level. Credit: Nature Genetics (2025). DOI: 10.1038/s41588-025-02249-4 Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression. The study, published in Nature Genetics, opens the door to developing new

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Altered FGFR1 pathway in hippocampus may underlie depression, especially in elderly

by The Korea Advanced Institute of Science and Technology (KAIST) edited by Lisa Lock, reviewed by Robert Egan Study methodology. Credit: Experimental & Molecular Medicine (2025). DOI: 10.1038/s12276-025-01519-9 Major depressive disorder (MDD) is one of the most common psychiatric illnesses worldwide, but its molecular causes have still not been clearly identified. A research team has discovered that depression may not

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New molecular mechanism offers hope for treating depression in the elderly

Download PDF Copy  Reviewed KAIST (Korea Advanced Institute of Science and Technology)Aug 25 2025 Major depressive disorder (MDD) is one of the most common psychiatric illnesses worldwide, but its molecular causes have still not been clearly identified. A domestic research team has discovered that depression may not simply be caused by neuronal damage, but can also arise

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Inflammation’s surprising role in diabetes and depression treatment

By Paul McClure August 09, 2025 Facebook Twitter Flipboard LinkedIn Reddit Email Inflammation affects how diabetics respond to depression treatment Depositphotos original extended using GenAI View 1 Images Inflammation may predict how well people with diabetes respond to depression treatment, and the effects differ dramatically between type 1 and type 2 diabetes, according to a new study

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Ibogaine treatment reduces PTSD, depression and anxiety in veterans with brain injuries

by Stanford University Medical Center edited by Gaby Clark, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain For military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head trauma or blast explosions are a leading cause of post-traumatic stress disorder, anxiety, depression and suicide among veterans. Few treatments have been

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Depression often associated with early menopause: Why some women are at greater risk

by The North American Menopause Society edited by Sadie Harley, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain Premature menopause has been described as a life-changing diagnosis with profound physical, psychological, and social consequences. Affected women not only experience the effects of estrogen deficiency, but they also experience the unanticipated loss of reproductive function. However, some women

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