psilocybin

A single dose of psilocybin is more effective than nicotine patches for quitting smoking, study suggests

by Krystal Kasal, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Image generated by the editorial team using AI for illustrative purposes. A new study, published in JAMA Network Open, reports the outcome of a clinical trial out of Johns Hopkins University assessing the effectiveness of psilocybin as a treatment […]

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Psilocybin could treat depression via a non-hallucinogenic receptor

by Ingrid Fadelli, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Illustration inspired by the topic of the paper. Credit: Angela Shang. Psychedelics, psychoactive substances that alter people’s perceptions, mood and thought patterns, have recently shown promise for the treatment of some mental health disorders, including depression and

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Analysis of ‘magic mushroom’ edibles finds no psilocybin but many undisclosed active ingredients

by Oregon State University edited by Sadie Harley, reviewed by Robert Egan Credit: Unsplash/CC0 Public Domain “Magic mushroom” edibles sold at smoke shops and convenience stores are likely to contain no psilocybin but instead a range of undisclosed active ingredients, a study led by an Oregon State University College of Pharmacy scientist shows. The research collaboration, which included a

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Can psychedelic mushrooms turn back the clock? Study suggests psilocybin preserves telomere length

by Graciela Gutierrez, Baylor College of Medicine edited by Robert Egan Psilocin treatment extends cellular lifespan. Human lung fibroblasts were treated continuously with vehicle (DMSO 0.02%) or 10 µM psilocin until they reached replicative senescence. Credit: npj Aging (2025). DOI: 10.1038/s41514-025-00244-x A compound found in psychedelic mushrooms may have antiaging properties. Researchers at Baylor College of Medicine have found that

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Could psilocybin help treat IBS? A new study investigates

Share on Pinterest Could magic mushrooms help relieve symptoms and treat IBS? A new study aims to find out. Irina Efremova/Stocksy Irritable bowel syndrome (IBS) is one of the most common conditions affecting the gut. Despite its prevalence and decades of research, treatments are limited, and the underlying causes remain shrouded in mystery. An ongoing

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Psilocybin and escitalopram produce antidepressant effects via distinct brain mechanisms, study suggests

by Eric W. Dolan  May 25, 2025 in Depression, Neuroimaging, Psilocybin   A new study published in the American Journal of Psychiatry sheds light on how psilocybin and the antidepressant escitalopram affect brain responses to emotional stimuli in people with major depressive disorder. While both treatments led to improvements in mood, only escitalopram was linked to a reduction in brain activity

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