Immunology

Aging dampens lupus by reducing overactive immune genes in older adults

July 29, 2025 / Clinical Practice, Immunology, liver treatment / InnovateMed Author / lupus, Systemic lupus erythematosus

by University of California, San Francisco edited by Sadie Harley, reviewed by Andrew Zinin Credit: CC0 Public Domain UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age. Lupus, an autoimmune disease, causes the immune system’s first-line viral defenses—known as interferons—to attack […]

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Immunotherapy alters bone marrow environment in acute myeloid leukemia patients

July 29, 2025 / Cancer, Immunology, Research update / InnovateMed Author / acute myleoid leukemia

by Virginia Tech edited by Sadie Harley, reviewed by Andrew Zinin Study scheme and analysis outline. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adw4871 Scientists studying a hard-to-treat form of blood cancer called acute myeloid leukemia (AML) have found that a type of treatment—immunotherapy—may help change the environment where cancer cells live, possibly helping the immune system respond more effectively. In a

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Specific immune cells linked to severe organ damage in systemic sclerosis

June 17, 2025 / Immunology, Research update / InnovateMed Author / immune cells, systemic sclerosis

by The University of Osaka edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Patients with scleroderma renal crisis demonstrated specific enrichment of CD14+ monocytes with increased EGR1 expression and activation of NF-κB–related pathways. Trajectory analysis indicated that they differentiated into macrophages and expressed high levels of THBS1 in the kidney. In patients with SSc-ILD, CD8+ effector

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Aging dampens lupus by reducing overactive immune genes in older adults

Immunotherapy alters bone marrow environment in acute myeloid leukemia patients

Specific immune cells linked to severe organ damage in systemic sclerosis

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