March 13, 2026

Improving AI models’ ability to explain their predictions

A new approach could help users know whether to trust a model’s predictions in safety-critical applications like health care and autonomous driving. Reports and ProceedingsMassachusetts Institute of Technology Cambridge, MA — In high-stakes settings like medical diagnostics, users often want to know what led a computer vision model to make a certain prediction, so they can […]

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Sleep apnea aggravates muscle loss in people with COPD, research shows

by Maria Fernanda Ziegler, FAPESP edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source A volunteer patient performs the six-minute walk test, which is used to assess functional capacity. Credit: UFSCar Chronic obstructive pulmonary disease (COPD) is known for causing breathing difficulties and limiting everyday activities. Obstructive sleep apnea syndrome (OSAS),

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Explore the human body in stunning, 3D detail with a new online tool

The free Human Organ Atlas gives users an up-close-and-personal look at 56 human organs. Laura Baisas Published Mar 11, 2026 2:00 PM EDT The Human Organ Atlas portal is open-access and includes the kidneys, brain, heart, and more. ESRF/UCL Get the Popular Science daily newsletter💡 Breakthroughs, discoveries, and DIY tips sent six days a week. Email address

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Dupilumab restores skin barrier function in children with moderate-to-severe atopic dermatitis, study shows

by National Jewish Health edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Clinical photographs of representative patient at baseline and week 16. TiVi = tissue viability imaging. Standardized photographs taken at baseline (upper left) and week 16 (upper right) and colorimetric images of the target lesion at baseline (lower left)

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New strategy intercepts pancreatic cancer by eliminating microscopic lesions before they become cancer

by Perelman School of Medicine at the University of Pennsylvania edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Effects of RAS(ON) inhibition on the pre-TME after 3 doses. Credit: Science (2026). DOI: 10.1126/science.aec7929 A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have

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Overlooked brainstem pathway that controls human hands offers stroke therapy targets

by Jules Bernstein, University of California – Riverside edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Organization of medullary and C3–C4 propriospinal systems underlying forelimb movement control in mice and humans. (A) Summary of cortical-medullary connectivity, particularly with Lat-RM and CauM, in forelimb movement control in mice. (B) Schematic representation

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Preclinical study reveals new cream may prevent or slow growth of some common skin cancers

Peer-Reviewed PublicationUniversity of Pennsylvania School of Medicine PHILADELPHIA – A topical cream activated the skin’s immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, according to a study published today in the Journal of Clinical Investigation. Developed by researchers at

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Intensive therapy approaches show benefits for infants and toddlers with cerebral palsy

by John Pastor, Virginia Tech edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source An infant participating in the Baby CHAMP study raises both hands while seated in a stroller. The NIH-funded trial led by the Fralin Biomedical Research Institute at VTC examines early therapies designed to improve arm and hand

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Differences in early Alzheimer’s brain markers across diverse populations appear in advanced PET brain scans

by Keck School of Medicine of USC edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source The colors show how much tau was detected in different parts of the brain. Blue marks areas with lower levels, while red marks areas with higher levels. Credit: USC/Stevens INI A team of researchers at

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Tuning T cells’ cancer-killing power via an engineered hydrogel platform

by Marni Ellery, University of California – Berkeley edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Diagram of T cell:dendritic cell immune synapse and PEGDA-Strep scaffold incorporating engagement of CD2 and LFA-1 during T cell activation. Credit: Advanced Materials (2026). DOI: 10.1002/adma.202505965 Lymph nodes, considered the command centers of our immune system,

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