March 10, 2026

Why lungs age unevenly: Vulnerable cells may guide new therapies

by Isabella Backman, Yale School of Medicine edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Overview of study design and single-cell RNAseq dataset. Credit: Nature Communications (2026). DOI: 10.1038/s41467-026-68810-9 Aging is associated with increased risk for nearly every lung disease, including acute conditions like pneumonia and chronic diseases like chronic obstructive pulmonary […]

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Study finds shared genetic roots of multiple sclerosis across diverse ancestries

by Queen Mary, University of London edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain A new study published in Neurology, led by Queen Mary University of London, has revealed that people of South Asian, African and European ancestry share many of the same genetic risk factors for multiple sclerosis

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Mouse brain study reveals why blockbuster weight-loss drugs may work differently in females and males

by Genomic Press edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Sex–specific Glp1 density in the medullary nucleus of the solitary tract (NTS). Representative RNAscope micrographs of medullary SolIM subnucleus of the NTS showing Glp1 expression (red arrows) in female and male mice. Credit: Mone Zaidi The drugs have

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Brain immune cells may help build Alzheimer’s plaques

by VIB (the Flanders Institute for Biotechnology) edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Fluorescent HiLyte647-labeled Aβ42 confirms the identity of cell-derived fibrillar deposits. Credit: Proceedings of the National Academy of Sciences (2026). DOI: 10.1073/pnas.2516774123 A new study led by researchers from VIB and KU Leuven shows that immune cells called

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Cannabis intoxication disrupts many types of memory

by Will Ferguson, Washington State University edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Carrie Cuttler, right, an associate professor in the Department of Psychology at WSU, points to a screen displaying data about caloric intake and THC, while Ryan McLaughlin, an associate professor in the Department of Integrative Physiology

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How post-stroke aphasia disrupts fluent speech

by Stephen Fontenot, University of Texas at Dallas edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source The overlaid lesion distribution map in the aphasia group (n = 20). Data show transverse slices in MNI (Montreal Neurological Institute) space, with warmer colors representing greater lesion overlap across participants (dark red areas

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Boron agents reach previously untreatable tumors

by Institute of Science Tokyo edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Institute of Science Tokyo Boron agents termed GluBs, developed by Science Tokyo researchers, have overcome a key limitation in cancer therapy by entering tumor cells through a pathway that standard drugs cannot use. The GluBs target

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Suicidality as a predictor of epilepsy med response

Psychiatric disorders are common among people with epilepsy. But a new study, published yesterday in JAMA Neurology, pinpoints suicidal ideation and attempts as unique predictors of a person’s response to antiseizure medications. Among nearly 350 participants in the Human Epilepsy Project, experiencing suicidality — whether or not it was accompanied by a mood or anxiety disorder

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Asian flush’ mutation may trigger ferroptosis during heart attacks, study reveals

by City University of Hong Kong (CityUHK) edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Professor Yin Huiyong, professor in the Department of Biomedical Sciences at CityUHK (right), and his research assistant, Dr Zhong Shanshan. Credit: City University of Hong Kong (CityUHK) About 40% of East Asians suffer from

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Q&A: How a tiny cellular portal could open vast possibilities for medicine

by Katherine Fenz, Rockefeller University edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain Inside each of your cells lies a nucleus, its master command center. Protected inside each nucleus are your chromosomes, containing all the genetic instructions for making proteins. To keep the body operating smoothly,

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