epilepsy

by National Yang Ming Chiao Tung University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Electroporation of shCtrl or shFoxj3, together with the GFP (green) construct, was performed at E12.5; brains were harvested at P7. Credit: the authors Researchers have discovered that mutations in the FOXJ3 gene act as

by Hebrew University of Jerusalem edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Green dots represent neuronal cells. Epileptic seizures induce pronounced neuronal cell loss. The upper panel shows a brain region from a rat experiencing seizures without treatment, whereas the lower panel shows the corresponding region following TXM-CB3 treatment,

Peer-Reviewed Publication King’s College London Credit: Unsplash/CC0 Public Domain An evidence-based web-app helped children with epilepsy to fall asleep on average 16.5 minutes earlier. A new UK-wide clinical trial led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has evaluated a self-guided behavioural sleep programme for the parents of children

by University of Pittsburgh edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: Unsplash/CC0 Public Domain For the first time, clinicians have access to a clear, evidence-based roadmap for adjusting antiseizure medication doses during pregnancy and after childbirth. The strategies, practiced by a group of leading women’s neurology experts in the nationwide landmark Maternal Outcomes and

by Georgetown University Medical Center edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain Temporal lobe epilepsy, which results in recurring seizures and cognitive dysfunction, is associated with premature aging of brain cells. A new study by researchers at Georgetown University Medical Center found that this form of epilepsy can be treated in

by Houston Methodist edited by Gaby Clark, reviewed by Robert Egan Editors’ notes Epilepsy Incidence Among Medicare Beneficiaries 65 Years and Older Across US MaxCounties. Credit: JAMA Neurology (2025). DOI: 10.1001/jamaneurol.2025.4347 A first-of-its-kind nationwide study has mapped epilepsy incidence rates among older adults in the United States and identified key social and environmental factors associated with the neurological condition. Published recently in JAMA

by Karen Guzman, Yale School of Medicine edited by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain Patients with treatment-resistant epilepsy often cycle through multiple medications as they seek relief from the seizures that disrupt their lives. Yet in many cases, these drugs offer little benefit, reinforcing the long-held belief among experts that treatment-resistant epilepsy is a

by Murdoch Children’s Research Institute edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain An advanced AI tool can detect tiny brain lesions that cause severe epilepsy in children, allowing faster diagnosis, more precise treatment and a potential cure, according to a new study. Developed by a team at Murdoch Children’s Research Institute