February 13, 2026

Researchers identify promising Alzheimer’s disease drug target

by Indiana University edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Hande Karahan and a team of researchers are investigating how targeting an enzyme in the brain’s neurons might reduce amyloid plaques and improve lipid metabolism in Alzheimer’s disease. Credit: Tim Yates, IU School of Medicine Indiana University School of […]

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New characteristics of aggressive prostate cancer identified

by Norwegian University of Science and Technology edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source This is what a frozen section of the prostate looks like. The researchers drilled small holes to extract tissue samples from areas where the gland contained cancer. It is precisely these tissue samples that were

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Understanding the difference between apathy and depression can be lifesaving for people with brain disorders

by Aderonke Agboji, Fiona MacDonald, The Conversation edited by Christopher Packham, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Tayla Walsh from Pexels People with brain disorders, including Parkinson’s disease and dementia, are often misdiagnosed as having depression, when in fact what they’re experiencing is apathy. This can delay an accurate diagnosis, which

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Scientists discover new gatekeeper cell in the brain

by VIB (the Flanders Institute for Biotechnology) edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source ChP base fibroblasts are present from early developmental stages and are derived from the meningeal mesenchyme. Credit: Nature Neuroscience (2026). DOI: 10.1038/s41593-025-02188-7 VIB and Ghent University researchers have identified and characterized a previously unknown cellular barrier in

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Researchers develop metastasis prevention therapy based on glycan targeting

by Hong Kong University of Science and Technology edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Hong Kong University of Science and Technology A research team led by Prof. Kenward Vong, Assistant Professor from the Department of Chemistry at The Hong Kong University of Science and Technology (HKUST) has

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Pancreatic cancer: Warning signs to heed

by Dpa edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain Your pancreas has important jobs to do. A large gland behind the lower part of the stomach, it produces hormones that regulate blood sugar

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Mitochondrial RNA may contribute to improved wound healing in diabetes

by Karin Broms, Karolinska Institutet edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Schematic of antioxidant defense and ROS homeostasis. Credit: Advanced Science (2026). DOI: 10.1002/advs.202517141 Diabetic foot ulcers are slow-healing and increase the risk of infections and amputation. Researchers at Karolinska Institutet have identified a circular RNA in mitochondria, circMTRNR2, that

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World-first toolkit puts autistic lens on suicide prevention

by La Trobe University edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain Researchers from La Trobe University have launched a world-leading toolkit for health care professionals to better identify and support Autistic adults at risk of suicide. One in three Autistic people experience suicidal thoughts, and

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Obamacare sign-ups drop, but the extent won’t be clear for months

by Julie Appleby edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain More Americans than expected enrolled in Affordable Care Act health insurance plans for this year, after premium subsidies were dramatically cut—but it remains to be seen whether they’ll keep the coverage as their costs

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Light-based sensor detects early molecular signs of cancer in the blood

by Optica edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Researchers developed a highly sensitive light-based sensor that can detect low concentrations of cancer biomarkers in the blood. When the biomarker is detected, the Cas12a protein used for CRISPR cuts the DNA holding the quantum dots, which causes a measurable

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