January 28, 2026

Targeting the gut’s immune system could tackle early stages of Parkinson’s

January 28, 2026 / Research update / InnovateMed Author / parkinson

Peer-Reviewed Publication University College London New research reveals how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK Dementia Research Institute at UCL (University College London). Scientists have long theorised that […]

Targeting the gut’s immune system could tackle early stages of Parkinson’s Read More »

Neuropathic bladder patients face complications after hip surgery

January 28, 2026 / Clinical Practice / InnovateMed Author / neuropathic bladder

by UT Southwestern Medical Center edited by Gaby Clark, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Patients with neuropathic bladder (NB), a condition in which nerve damage affects bladder function, have a significantly higher risk of joint infections, blood clots, and other adverse events after receiving total hip replacement (THR),

Neuropathic bladder patients face complications after hip surgery Read More »

Research reveals how the brain turns experience into memory—with help from a tiny protein

January 28, 2026 / Research update / InnovateMed Author / protein

by Stowers Institute for Medical Research edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Electron microscopy image of Orb2 amyloid fibers. Red arrows indicate the chaperone protein Funes aiding in the assembly of Orb2 amyloid. Credit: Stowers Institute for Medical Research Why some memories persist while others vanish has fascinated

Research reveals how the brain turns experience into memory—with help from a tiny protein Read More »

Smoking, blood pressure and diabetes each show distinct dementia-related brain changes

January 28, 2026 / Clinical Practice / InnovateMed Author / smoking

by Åsa Hansdotter, Lund University edited by Gaby Clark, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Credit: Pexels LATAM from Pexels Almost half of all dementia cases can be attributed to risk factors that we can potentially influence ourselves, such as smoking and high blood pressure. A new study from Lund University shows

Smoking, blood pressure and diabetes each show distinct dementia-related brain changes Read More »

How your life story leaves epigenetic fingerprints on your immune cells

January 28, 2026 / Research update / InnovateMed Author / immune cells

by Salk Institute edited by Stephanie Baum, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Overview of the study. For HIV-1 and IAV, we have internal control samples that are from the same set of donors before infection and collected samples from them after exposure. We also collected PBMC from 12 healthy donors as

How your life story leaves epigenetic fingerprints on your immune cells Read More »

Scientists develop first gene-editing treatment for skin conditions

January 28, 2026 / Research update / InnovateMed Author / skin condition

by Brett Goldhawk, University of British Columbia edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Dr. Sarah Hedtrich (right) with members of her team in the lab. Credit: UBC Faculty of Medicine Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the University of

Scientists develop first gene-editing treatment for skin conditions Read More »

Sleeping without pillows may lower harmful high internal eye pressure in people with glaucoma

January 28, 2026 / Clinical Practice / InnovateMed Author / glaucoma

by British Medical Journal edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Sleeping without pillows may help lower high internal eye pressure, the build-up of which causes optic nerve damage and glaucoma—the leading cause of irreversible blindness worldwide—in people with the condition, suggests preliminary research, published

Sleeping without pillows may lower harmful high internal eye pressure in people with glaucoma Read More »

Antibody-producing immune cells can help shape cancer immunotherapy

January 28, 2026 / Research update / InnovateMed Author / cancer immunotherapy

by The Mount Sinai Hospital edited by Gaby Clark, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Discovery cohort and the establishment of a plasma IgG1 isotype. Credit: Nature Medicine (2026). DOI: 10.1038/s41591-025-04177-6 Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients

Antibody-producing immune cells can help shape cancer immunotherapy Read More »

Researchers identify genetic blueprint of mania in bipolar disorder

January 28, 2026 / Research update / InnovateMed Author / mania

by Alex Booth, King’s College London edited by Stephanie Baum, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain For the first time, researchers at King’s College London and the University of Florence have identified the specific genetic blueprint of mania, the defining feature of bipolar disorder. Bipolar disorder is one

Researchers identify genetic blueprint of mania in bipolar disorder Read More »

Magnetic pulses to the brain emerge as low-cost lifeline for depression

January 28, 2026 / Clinical Practice / InnovateMed Author / depression

by University of Nottingham edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Credit: CC0 Public Domain A major new study has found that transcranial magnetic stimulation (TMS), which applies magnetic energy to the brain, can be a cost-effective treatment option for the NHS in treating moderate and severe forms of

Magnetic pulses to the brain emerge as low-cost lifeline for depression Read More »