January 23, 2026

Progenitor cells constantly attempt to produce new myelin-producing brain cells, study finds

by Johns Hopkins University School of Medicine edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source “Dandelion-clock-like structures,” or DACS, formed when oligodendrocyte precursor cells attempt to differentiate. Credit: Yevgeniya Mironova, Ph.D. In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one of the few […]

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Breast cancer study reveals synergistic effect of CDK2 and CDK4/6 combination therapy

by University of Texas MD Anderson Cancer Center edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously targeting two key

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New study reveals widespread liver dysfunction in Down syndrome, suggests link to diet

by University of Colorado Anschutz edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Cell Reports (2026). DOI: 10.1016/j.celrep.2025.116835 Researchers at the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) have uncovered compelling evidence that individuals with Down syndrome experience significant alterations in liver metabolism, including elevated levels

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Discovery illuminates how inflammatory bowel disease promotes colorectal cancer

by Weill Cornell Medical College edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Enhanced image showing where genes are active in colon tissue, revealing neutrophils located close to pre-cancerous epithelial cells. Credit: Longman lab. A chain of immune reactions in the gut—driven by a key signaling protein and a surge of

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Alzheimer’s disease can be evaluated with brain stimulation, finds study

by Gina DiGravio, Boston University School of Medicine edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source A and B: TMS evoked potentials (TEPs) from HC and AD representative subjects with selected peaks (color vertical lines) demonstrated in the topographies are of selected time points. Credit: Neuroscience of Consciousness (2026). DOI: 10.1093/nc/niaf062 As

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Early intervention helps most autistic children acquire spoken language

by Drexel University edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain After receiving evidence-based early interventions, roughly two-thirds of non-speaking kids with autism speak single words, and approximately half develop more complex language, according to a new study led by researchers at Drexel University’s A.J. Drexel

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A balancing act: Dual mRNA markers in T cells act as a kill switch to prevent an overactive immune system

by The Francis Crick Institute edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Cytokines released by T cells after encountering cancer cells. Credit: Iosifina Foskoulo How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy cells? Research into an immune kill

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Gut bacteria may be linked to memory decline in mild cognitive impairment and Alzheimer’s disease

by George Washington University edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Venn diagram summarizing unique and common attributes among individuals with Alzheimer’s disease (AD), mild cognitive impairment (MCI), and healthy controls. Credit: Alzheimer’s & Dementia (2026). DOI: 10.1002/alz.71023 A comprehensive new review is shedding light on the growing evidence that gut

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Stanford scientists found a way to regrow cartilage and stop arthritis

Scientists have found a way to regrow aging cartilage, raising hopes for arthritis treatments that could make joint replacements obsolete. Date: January 20, 2026 Source: Stanford Medicine Summary: Scientists at Stanford Medicine have discovered a treatment that can reverse cartilage loss in aging joints and even prevent arthritis after knee injuries. By blocking a protein

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