immune system

Why our immune system remembers vaccinations for decades

by Friedrich–Alexander University Erlangen–Nurnberg edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Why can the human immune system often remember a vaccination for a whole lifetime? Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen have now investigated this question. Their study provides a surprisingly clear answer: […]

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New research connects heart attacks to brain, nervous and immune systems

Uncovering ‘three node’ links opens a path to new treatments for world’s leading cause of death Peer-Reviewed PublicationUniversity of California – San Diego image: UC San Diego scientists have uncovered a new understanding of heart attacks. The research, which connects the heart, brain and nervous and immune systems, opens a path to new treatments for

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A balancing act: Dual mRNA markers in T cells act as a kill switch to prevent an overactive immune system

by The Francis Crick Institute edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Cytokines released by T cells after encountering cancer cells. Credit: Iosifina Foskoulo How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy cells? Research into an immune kill

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Certain antibiotics may may boost immune system

by Lancaster University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Graphical Abstract. Credit: Discovery Immunology (2025). DOI: 10.1093/discim/kyaf018 Research led by Lancaster University has discovered that a class of antibiotics—fluoroquinolones—can directly alter the potential bacterial killing ability of one of our immune cells called the macrophage. Our lungs must balance the

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Dormant cancer cells can change shape to survive immune system attack

by Ian Demsky, Memorial Sloan Kettering Cancer Center edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Dormant lung cancer cells change their shape from spindle-shaped (above) to round (below), which helps protect them from the body’s immune defenders. Credit: Wang, Z., et al., Nature Cancer (CC BY 4.0) Cancer cells

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Fat surrounding the colon interacts with the immune system, findings suggest

by Karolinska Institutet edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain Abdominal fat is not a uniform tissue. A new study from Karolinska Institutet, Steno Diabetes Center Copenhagen, and Helmholtz Munich reveals that fat located close to the large intestine contains an unusually high number of

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Tattoos, toxins and the immune system—what you need to know before you get inked

by Manal Mohammed, The Conversation edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain From minimalist wrist designs to full sleeves, body art has become so common that it barely raises an eyebrow. But while the personal meaning of a tattoo may be obvious, the biological consequences are far less visible. Once tattoo

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Crucial protein enables immune system memory

by University of Missouri edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Confirmation of POSH deletion in POSHfl/fl CD4-Cre mice. (A) Schematic depicting the original SH3rf1tm1a(EUCOMM)Hmgu genetic construct (top) and the construct after deletion of the luciferase/neo cassette (bottom) for the POSHfl/fl gene (B, C) GFP positive T cells were isolated, lysed, and mRNA and protein were isolated. (B) Deletion of exon 7 from the

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AI tool offers deep insight into the immune system

Immunology research boosted with a technique based around image analysis Peer-Reviewed Publication University of Tokyo image: An overview of the process linking single-cell RNA input, image conversion and CNN analysis, to hierarchical immune cell classification. ©2025 Tsunoda et al. CC-BY-ND view more  Credit: ©2025 Tsunoda et al. CC-BY-ND Researchers explore the human immune system by looking

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How does your immune system stay balanced? A Nobel Prize-winning answer

by Aimee Pugh Bernard, The Conversation edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Regulatory T cells suppress immune responses using a variety of molecular signals. Credit: Giwlz/Wikimedia Commons, CC BY-SA Every day, your immune system performs a delicate balancing act, defending you from thousands of pathogens that cause disease while sparing your body’s own healthy cells. This careful

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