January 14, 2026

Personalized prevention strategies may lower Alzheimer’s risk by targeting individual factors

by Theo von Däniken, University of Zurich edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source The mediating effect of gray matter (GM) atrophy is more pronounced in individuals with high socioeconomic status (SES) because of faster amyloid-beta (Aβ)-related GM atrophy rates. Credit: Annals of Neurology (2025). DOI: 10.1002/ana.70022 How can we influence […]

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Study finds early withdrawal of care may limit recovery in severe brain injury

by Anastasia (Ana) Gorelova, University of Pittsburgh Schools of the Health Sciences edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain A new study led by University of Pittsburgh School of Medicine clinical scientists and UPMC neurosurgeons challenges assumptions about early withdrawal of care in patients with

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Physician group releases guideline on biologic management in severe asthma

by American College of Chest Physicians edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain The American College of Chest Physicians recently released a new clinical guideline on biologic management in severe asthma. Published in the journal CHEST, the guideline contains seven evidence-based recommendations to provide a framework for pulmonologists,

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Blood metabolite signature offers improved prediction of type 2 diabetes risk

by Mass General Brigham edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain Diabetes, a metabolic disease, is on the rise worldwide, and over 90% of cases are type 2 diabetes, where the body does not effectively respond to insulin. Researchers from Mass General Brigham and Albert

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What’s the difference between a sprained ankle and a twisted ankle?

by Hunter Bennett, Lewis Ingram, The Conversation edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Kindel Media/Pexels After the summer break, you’re ready to get back into exercise. You put on your shoes, pop on your headphones and head out the door on your first run of the new

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Diabetes risk not associated with timing or type of menopause

by The North American Menopause Society edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Women aged younger than 45 years who experience menopause are at a higher risk of coronary heart disease and stroke. However, despite such diabetes-related risk factors as increased fat and insulin resistance

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Implant provides lasting relief for treatment-resistant depression, study finds

by Shawn Ballard, Washington University in St. Louis edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Sara Moser / Washu Medicine About 20% of U.S. adults experience major depression in their lifetime. For most people, symptoms improve within a few treatment attempts, but up to one‐third of patients have

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The aggressive use of antibiotics could fuel mood disorders and anxiety

by Ingrid Fadelli, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Consistent decline of acetylcholine in the microbiota-gut-brain axis. A) acetylcholine levels were significantly reduced in the feces, colon, blood, and hippocampus; B) Strong correlations were observed between acetylcholine levels in peripheral samples (feces, colon, blood) and central

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More than just fear: A new profile of post-traumatic stress disorder

by Eva Cornman, Yale University edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Kindel Media from Pexels Trauma may be even more complex than previously thought. Post-traumatic stress disorder (PTSD) is often portrayed in popular media as subjects experiencing hypervigilance, flashbacks, and nightmares. While these fear-based symptoms do commonly

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Blood test predicts which patients with lung cancer will benefit from newly approved immunotherapy drug

by Mass General Brigham edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Artem Podrez from Pexels A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will

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