January 14, 2026

Over-the-counter medications may alter cancer immunotherapy outcomes

January 14, 2026 / Research update / InnovateMed Author / counter medication

by Matt Talhelm, Duke University edited by Gaby Clark, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Two patients who are being treated with immunotherapy for identical cancers may exhibit differential responses due to taking different medications. PPI, proton pump inhibitor; TMB, tumor mutational burden. Credit: Journal of Clinical Oncology (2026). DOI: 10.1200/jco-25-01811 Immunotherapy is offering […]

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When a virus releases the immune brake: New evidence on the onset of multiple sclerosis

January 14, 2026 / Immunology, Research update / InnovateMed Author / multiple sclerosis

by University of Basel edited by Gaby Clark, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Antigen surveillance by B cells. Credit: Cell (2026). DOI: 10.1016/j.cell.2025.12.031 Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself. Yet for most of them, it remains unclear why this process begins. Researchers have

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How exercise helps aging muscles repair themselves

January 14, 2026 / Clinical Practice / InnovateMed Author / aging

by Duke-NUS Medical School edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source As we age, higher DEAF1 levels cause damaged proteins to build up in muscle cells, leading to muscle aging and weakness. Exercise keeps aging muscles healthy by lowering DEAF1 levels and restoring balance in muscle growth and repair.

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Tiny sensor could transform head injury detection

January 14, 2026 / Research update / InnovateMed Author / injury detection

by King Abdullah University of Science and Technology edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Application of the inertial switch in sports to immediately detect possible brain injuries. Credit: Scientific Reports (2025). DOI: 10.1038/s41598-025-21637-8 A tiny sensor that detects hazardous head impacts the instant they occur could reshape safety monitoring in

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Blocking key enzyme to protect against fatty liver may raise cancer risk instead

January 14, 2026 / Research update / InnovateMed Author / Fatty liver

by University of Adelaide edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age. In a major study published in Science

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Smartphone apps triple long-term quit rates compared to minimal smoking cessation support

January 14, 2026 / Clinical Practice / InnovateMed Author / smoking

by British Medical Journal edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Smartphone apps—particularly those based on psychological theories—are three times as effective as no/minimal support at helping people who smoke stub out their tobacco use long term, suggests a pooled data analysis of the available

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Schizophrenia: The cerebellum’s unexpected role

January 14, 2026 / Research update / InnovateMed Author / schizophrenia

by University of Geneva edited by Gaby Clark, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Illustrative image of the connectivity between the cerebellum and the VTA. Credit: Thomas Bolton Apathy, social withdrawal, and loss of motivation—the so-called ”negative” symptoms of schizophrenia—are among the most disabling and hardest to treat. A team from the

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Five healthy habits for longevity in your 40s and 50s

January 14, 2026 / Patient education / InnovateMed Author / longevity

by Sarah Williams, Stanford University edited by Sadie Harley, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain The choices you make in midlife have an outsized impact on your long-term health, Stanford Medicine specialists say. You might feel like you’re hitting your stride in your 40s and 50s—you’ve established a

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Screening tool helps identify brain-related comorbidities in individuals with Duchenne muscular dystrophy

January 14, 2026 / Research update / InnovateMed Author / Duchenne Muscular Dystrophy

by Wiley edited by Stephanie Baum, reviewed by Andrew Zinin Editors’ notes The GIST Add as preferred source Histopathology of gastrocnemius muscle from patient who died of pseudohypertrophic muscular dystrophy, Duchenne type. Cross section of muscle shows extensive replacement of muscle fibers by adipose cells. Credit: Wikimedia Commons/Public Domain In research published in Developmental Medicine & Child Neurology, investigators have developed

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Mapping gene disruptions in sporadic early onset Alzheimer’s disease across key brain regions

January 14, 2026 / Research update / InnovateMed Author / alzheimer

by Sydney Lowther, University of Texas Health Science Center at Houston edited by Gaby Clark, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Single-nucleus multiome assays characterized cell type–specific expression and regulation in the three brain regions in individuals with sEOAD. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adw4917 A new study led by researchers at UTHealth Houston

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