November 13, 2025

Gut bacterium may sabotage liver cancer immunotherapy, study suggests

by The University of Hong Kong edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Cell Reports Medicine (2025). DOI: 10.1016/j.xcrm.2025.102370 A research team led by the Department of Clinical Oncology, Center of Cancer Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified a critical factor contributing to the failure […]

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Disrupted calcium signaling can throw the heart off rhythm

by Lena Bösch, University Medical Center Göttingen edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Circulation Research (2025). DOI: 10.1161/circresaha.124.325658 A joint study by the University Medical Center Göttingen (UMG) and the University Hospital Würzburg provides new insights into why heart muscle cells lose their rhythm in atrial fibrillation. Disrupted calcium signaling between key cellular structures in

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Why type 1 diabetes is more aggressive in young children

by Louise Vennells, University of Exeter edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes AI-assisted WSI analysis performed to investigate the development of the endocrine architecture postbirth during pancreas expansion. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adz2251 Scientists have made a major breakthrough in understanding why type 1 diabetes is more aggressive in young children, offering the clearest explanation

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Researchers try bold new approach in a race to better treat autoimmune diseases

by Lauran Neergaard edited by Andrew Zinin  Editors’ notes Dr. Maximilian Konig, a rheumatologist at Johns Hopkins University, sits for a portrait in the lab where he’s studying some possible new treatments for autoimmune diseases, Tuesday, May 13, 2025, in Baltimore, Md. Credit: AP Photo/David Goldman Scientists are trying a revolutionary new approach to treat rheumatoid

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Enzyme provides promising path to degenerative joint diseases cure

by John Ready, Yale University edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Deletion of cPLA2 protects against surgically-induced OA. Credit: Bone Research (2025). DOI: 10.1038/s41413-025-00470-9 Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current treatments manage symptoms

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The link between the gut microbiome and autism is not backed by science, researchers say

by Cell Press edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain There’s no scientific evidence that the gut microbiome causes autism, a group of scientists argue in an opinion paper published in Neuron. They point to the fact that conclusions from past research that supported this hypothesis—including observational studies, mouse models of autism, and human

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Natural molecule reverses memory loss seen in Alzheimer’s disease

By Bronwyn Thompson November 12, 2025 Facebook Twitter LinkedIn Reddit Flipboard Email Scientists identify a new weapon in restoring memory to Alzheimer’s disease patients Robina Weermeijer/Unsplash View 2 Images Boosting levels of a certain molecule that declines with age was found to restore memory and brain function in Alzheimer’s disease (AD) models – not just by

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Mounjaro: What is the ‘golden dose’ and what are the risks?

The “golden dose” left in Mounjaro or Ozempic pens may do more harm than good, according to experts. Design by MNT; Photography by Bloomberg/Getty Images Over the last few years, the interest in GLP-1 drugs for weight loss has skyrocketed. Currently, the most common delivery system for GLP-1 medications is through pre-filled injection pens designed

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Scientists tie lupus to a virus nearly all of us carry

by Stanford University Medical Center edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes This electron microscopic image of two Epstein Barr Virus virions (viral particles) shows round capsids—protein-encased genetic material—loosely surrounded by the membrane envelope. Credit: PloS Biology (2005), DOI: 10.1371/journal.pbio.0030430.g001 One of humanity’s most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic

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States scramble to avoid Medicaid shortfalls

  By Adriel Bettelheim Illustration: Sarah Grillo/Axios Rising health costs and nearly $1 trillion of cuts to federal Medicaid spending are forcing states to scramble in order to keep their Medicaid programs from slipping into the red, an annual survey of state officials finds. Why it matters: Some are responding by imposing new limits on how they pay health providers

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