type 1 diabetes

Stanford Cures Type-1 Diabetes in Mice Without Insulin or Immune-Suppression

Study team members Stephan Ramos, Seung Kim, and Preksha Bhagchandani – credit, Steve Fisch, Stanford UniversityIn an experiment that exceeded scientists’ expectations, mice had their type-1 diabetes cured through a double-transplant method. Additionally, there was no host rejection of one one of the two types of transplanted cells, and the immune system didn’t attack the […]

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Nanoparticle system shows promise for delivering mRNA to prevent type 1 diabetes

by University of Chicago Medical Center edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Cell Reports Medicine (2026). DOI: 10.1016/j.xcrm.2026.102634 Research on preventing type 1 diabetes often focuses on limiting the autoimmune response that destroys the body’s ability to produce its own insulin. A new technology developed by scientists at the

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Groundbreaking Trial Reveals Unexpected Benefit of Metformin in Type 1 Diabetes

By Garvan Institute of Medical ResearchMarch 1, 20264 Comments6 Mins Read A widely used, low-cost drug may be poised to reshape how type 1 diabetes is managed. In a carefully controlled clinical trial, researchers discovered that while the medication doesn’t work in the way many assumed, it still delivers a meaningful benefit: reducing the amount of

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Researchers find vital clue in the progression of Type 1 diabetes

by Bill Levesque, University of Florida edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes This is a microscopic view of islets of insulin-producing beta cells from a human pancreas, shown using immunofluorescent staining. The islets are green. Credit: Clive Wasserfall and Denise Drotar Type 1 diabetes is a disease in which the body mistakenly attacks itself

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How a cheap, century-old drug can improve life with type 1 diabetes

by Garvan Institute of Medical Research edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Artem Podrez from Pexels A Garvan-led clinical trial has found that using a common and inexpensive type 2 diabetes drug reduces insulin needs in type 1 diabetes, opening doors for improved management of the condition. For years, doctors have prescribed metformin,

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Low-Fat Vegan Diet Cuts Insulin Use and Costs in Type 1 Diabetes

Nancy A. Melville November 20, 2025 A low-fat vegan diet with no restrictions on calories or carbohydrates led to significant reductions in insulin use and body weight among adults with type 1 diabetes (T1D), lowering daily insulin costs compared with a standard portion-controlled diet, according to new research. “This lower insulin use on the low-fat

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Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant by Krista Conger, Stanford University Medical Center edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Graphical abstract. Credit: Journal of Clinical Investigation (2025). DOI: 10.1172/jci190034 A combination of blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or

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Why type 1 diabetes is more aggressive in young children

by Louise Vennells, University of Exeter edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes AI-assisted WSI analysis performed to investigate the development of the endocrine architecture postbirth during pancreas expansion. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adz2251 Scientists have made a major breakthrough in understanding why type 1 diabetes is more aggressive in young children, offering the clearest explanation

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Sons of mothers with type 1 diabetes show early signs of vascular dysfunction

by Felicia Lindberg, Karolinska Institutet edited by Gaby Clark, reviewed by Robert Egan Graphical abstract. Credit: Cell Reports Medicine (2025). DOI: 10.1016/j.xcrm.2025.102454 A new study from Karolinska Institutet and Stockholm University reveals that sons born to mothers with type 1 diabetes may develop early vascular dysfunction—independently of metabolic health. The finding may help shape future strategies to prevent cardiovascular disease

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Type 1 diabetes causes, symptoms, diagnosis and treatment

by Brittany Bruggeman and Chineze Ebo edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain Each November, we observe National Diabetes Month and engage in discussions surrounding prevention, management and the impact of this increasingly common autoimmune disease. Diabetes, both type 1 and type 2, are conditions that affect the way the

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