November 3, 2025

Long-term study challenges assumptions about epilepsy recovery

by Karen Guzman, Yale School of Medicine edited by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain Patients with treatment-resistant epilepsy often cycle through multiple medications as they seek relief from the seizures that disrupt their lives. Yet in many cases, these drugs offer little benefit, reinforcing the long-held belief among experts that treatment-resistant epilepsy is a […]

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FDA to ease copycat drug rules, speeding access to cheaper drugs

by I. Edwards edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes The U.S. Food and Drug Administration (FDA) announced Wednesday that it will relax certain rules for approving low-cost versions of some high-priced medications, in an effort to speed up access to cheaper alternatives. The decision affects biosimilars—medicines that are near-identical copies of biologic drugs

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Dietary fiber, prunes and senna offer relief for constipation discomfort

by Barbara Intermill edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain Big-gun pain relievers can come with unwelcome side effects. At the top of the list for many of these products are constipation and the distress of slowed bowels. In general, the basic instruction to prevent these maladies is to increase

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Can a weight loss and diabetes drug treat long COVID?

by Paul Sisson edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: Anna Tarazevich from Pexels Scripps Research in La Jolla announce a new clinical trial that will assess the effectiveness of using drugs approved for diabetes treatment and weight loss to treat long COVID-19, the debilitating chronic condition diagnosed in an estimated 20 million

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Why I Want My Patients to Add Food, Not Subtract

Brandy W. Root, RDN DISCLOSURES October 14, 2025 We used to tell patients with high cholesterol to avoid meat and dairy and to throw away their egg yolks. This advice was so common that even former President Bill Clinton adopted a vegan diet to treat his cardiovascular disease. We now know that, although limiting those foods can be

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Prediabetes Remission Possible Even Without Weight Loss

Stephanie Brown October 29, 2025 People with prediabetes are encouraged to lose 5%-7% of their body weight to prevent progression to type 2 diabetes. However, your patients might become discouraged if they don’t see the number on the scale drop. New findings published in Nature Medicine showed that people can enter prediabetes remission — and lower type 2 diabetes risk

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Anti-Obesity Medications Set to Explode Entering 2026

Julie Peck October 22, 2025 29 2550 With the supply of GLP-1 medications finally stabilizing as their use skyrocketed 600% among Americans from 2018 to 2024, the pharmaceutical landscape for anti-obesity medications is now poised to undergo another monumental shift. A rapid proliferation of drugs that show an unprecedented efficacy for treating this disease is expected

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Weight loss drugs improve heart health regardless of amount of weight lost: study

A new study finds that GLP-1 drugs’ heart health benefits may not be solely due to weight loss. The Good Brigade/Getty Images As the popularity of GLP-1 receptor agonists for weight loss continues to grow, researchers continue to examine how these medications might impact other areas of a person’s health. In 2023, published research findings

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What PCPs Need to Know About the New Blood Pressure

Okay, it doesn’t get any bigger than this! Today we’re going to discuss the new guideline on hypertension from the American College of Cardiology [ACC] and American Heart Association [AHA]. These guidelines are endorsed by a boatload of organizations, but not the AAFP (the American Academy of Family Physicians), the ACP (American College of Physicians), or the ISH (the

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