Weight loss

Most weight lost on GLP-1 drugs returns within a year after stopping

By Dr. Liji Thomas, MDReviewed by Lauren HardakerMar 9 2026 Stopping popular GLP-1 weight-loss drugs may reverse much of their benefit within a year, according to a large modeling analysis, raising questions about how long patients may need to stay on treatment to sustain meaningful weight loss.  Study: Trajectory of weight regain after cessation of GLP-1 receptor agonists: […]

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If you’re struggling to lose weight, could chilling your carbs help?

by J.m. Hirsch edited by Alexander Pol  Editors’ notes  The GIST Add as preferred source Grains of uncooked jasmine rice appear in Harrisburg, Pa., on April 24, 2008. Credit: AP Photo/Carolyn Kaster, File Online influencers claim the secret to low-calorie rice, pasta and potatoes may be as simple as chilling out. Are they right? Not quite.

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Triggering self-combustion in fat cells for weight loss

by Jim Schnabel, Cornell University edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Models of different types of coupled and uncoupled respiration. Credit: Nature Metabolism (2026). DOI: 10.1038/s42255-026-01467-2 Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to a preclinical study by Weill Cornell

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MCT Oil Benefits for Weight Loss, Metabolism, and Fat Burning

By Hugo Francisco de SouzaReviewed by Benedette Cuffari, M.Sc. Introduction What is MCT oil? MCT structure and metabolism Effects on energy expenditure Effects on fat oxidation Mechanisms of action Considerations and limitations Practical takeaways Conclusions References Further reading Medium-chain triglycerides are rapidly absorbed fats that increase postprandial energy expenditure, enhance fat oxidation, and stimulate ketogenesis, with modest

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Taking the next shot: GLP-1 research and the new era of weight loss

by Noelle Toumey Reetz, Georgia State University edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Eric Krause, a professor of neuroscience and Georgia Research Alliance distinguished investigator, studies how GLP-1 therapies affect brain pathways, weight loss and muscle mass. Credit: Georgia State University Soaring in popularity, GLP-1 medications—from weekly injections

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Weight-loss wonder pills prompt scrutiny of their key ingredient

by University of Adelaide edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Journal of Controlled Release (2026). DOI: 10.1016/j.jconrel.2026.114711 Blockbuster weight-loss drugs are transforming the way we treat obesity. But while costly injectable versions remain out of reach for many, newly approved tablet forms are expected to significantly boost access and

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Could being a night owl or early bird affect weight loss and muscle strength?

A person’s biological clock and chronotype, as well as their lifestyle habits, may influence their health in the long run. Raymond Forbes LLC/Stocksy According to a new review, understanding your biological clock and chronotype might help you build muscle and lose weight more effectively. Working with, rather than against, your chronotype — such as being

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Rethinking weight loss in the Ozempic era: Researchers urge a more holistic view

by George Mason University edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain In the world of obesity research, the arrival of GLP-1 drugs like Ozempic feels seismic. At a recent conference, Martin Binks, a leader in obesity research, found himself marveling with a colleague: “Can you

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Can you really lose weight by cutting gluten from your diet, as Matt Damon claims?

by Guy Guppy, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain When Matt Damon recently credited his weight loss to going gluten-free, it reignited a familiar debate about this divisive dietary approach. But while The Odyssey star’s claims have sparked discussion, the science behind

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New study: How weight loss benefits the health of your fat tissue

Shedding pounds almost invariably brings health benefits. But until now, it has been unclear to what extent weight loss also restores the health of the fat tissue itself. A new study from University of Southern Denmark offers insights into the profound ch Peer-Reviewed Publication University of Southern Denmark image: Changes in adipose tissue during weight

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