November 3, 2025

Health Implications of p‑Phenylenediamine: The Aromatic Amine in Permanent Hair Dye

November 3, 2025 / Patient education / InnovateMed Author / hair dye

By Hugo Francisco de SouzaReviewed by Benedette Cuffari, M.Sc. Introduction How PPD works in permanent hair dyes Health implications of PPD use in cosmetics Toxicological profile and systemic risks Regulatory status and safety assessments Safer alternatives and future directions Conclusions References Further reading This article explains how p-phenylenediamine (PPD) is used in permanent hair dyes, its health […]

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What is Vaginismus? A Guide for Women’s Sexual Health

November 3, 2025 / Clinical Practice / InnovateMed Author / vaginismus

By Hugo Francisco de SouzaReviewed by Benedette Cuffari, M.Sc. Introduction What is vaginismus? Etiology and risk factors Clinical presentation and diagnosis Therapeutic approaches Prognosis and long-term outcomes Conclusions References Further reading Vaginismus involves involuntary pelvic floor muscle tightening that makes penetration painful or impossible, often linked to fear, anxiety, or past trauma. Effective multidisciplinary treatments, including physical

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New switch for programmed cell death identified

November 3, 2025 / Research update / InnovateMed Author / cell death

Successful basic research at TUM for combating severe diseases Peer-Reviewed Publication Technical University of Munich (TUM) The activation and deactivation of apoptosis is a promising field of research in basic biomedical research. The team led by Prof. Franz Hagn from the Chair of Structural Membrane Biochemistry at the TUM School of Natural Sciences has now discovered a new switch:

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Researchers pinpoint target for treating virus that causes the stomach bug

November 3, 2025 / Research update / InnovateMed Author / stomach bug

New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Peer-Reviewed Publication University of California – Santa Cruz image: Adam Lentz, a Ph.D. student in the DuBois lab at UC Santa Cruz, led a project to better understand the structure of human astroviruses. view more Credit: Rebecca

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Researchers unveil a powerful new gene-switch tool

November 3, 2025 / Research update / InnovateMed Author / new gene

Peer-Reviewed Publication Weill Cornell Medicine image: Dr. Samie Jaffrey view more Credit: Weill Cornell Medicine Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such “gene-switch” tools allow scientists to “turn on” or “turn off” a target gene to study how it works,

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Analyzing 3 biomarker tests together may help identify high heart disease risk earlier

November 3, 2025 / Research update / InnovateMed Author / heart disease

American Heart Association Scientific Sessions 2025 Abstract Poster MP2285 Reports and Proceedings American Heart Association Research Highlights: Adults with elevated levels of three biomarkers for heart disease—lipoprotein a (also called Lp(a)), remnant cholesterol and high-sensitivity C-reactive protein (hsCRP)—had nearly triple the risk of heart attack compared to those without elevated levels. In addition, people with

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145 families receive a diagnosis with new genomic method

November 3, 2025 / Research update / InnovateMed Author / genomic method

Experts have developed a new method for identifying structural changes in DNA, providing insights for ~145 families and highlighting the importance of incorporating these changes into clinical practice. Peer-Reviewed Publication Wellcome Trust Sanger Institute A new genomic method has enabled multiple people with rare conditions to receive diagnoses that were previously unattainable by identifying complex

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Scientists build detailed map of the developing human brain, opening new pathways for Parkinson’s treatment

November 3, 2025 / Research update / InnovateMed Author / parkinson

Duke-NUS scientists have built one of the largest and most comprehensive maps of the developing human brain, marking a major step forward in testing new therapies for Parkinson’s disease and other neurological conditions Peer-Reviewed Publication Duke-NUS Medical School image: Midbrain dopaminergic neurons under a microscope view more Credit: Hilary Toh, Duke-NUS Medical School SINGAPORE, 03 NOVEMBER

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Long-term use of melatonin supplements to support sleep may have negative heart health effects

November 3, 2025 / Research update / InnovateMed Author / melantonin

by American Heart Association edited by Sadie Harley, reviewed by Robert Egan Editors’ notes Credit: Unsplash/CC0 Public Domain Long-term use of melatonin supplements, often used to promote sleep and address insomnia, is associated with a higher risk of heart failure diagnosis, heart failure, hospitalization and death from any cause in chronic insomnia, according to a preliminary study presented

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Running ‘super shoes’ may make you faster—but at what cost?

November 3, 2025 / Patient education / InnovateMed Author / running super shoes

by Joel Fuller, Chloe Blacket, Eoin Doyle, John Arnold, The Conversation edited by Lisa Lock, reviewed by Andrew Zinin Editors’ notes Credit: Pixabay/CC0 Public Domain Once seen only on the feet of elite runners at the Olympics and other premier running events, the so-called “super shoe” has moved from racing podiums to pavements. Today, you’re just about as

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