August 27, 2025

AI reveals how protein modifications link mutations to disease

August 27, 2025 / Research update / InnovateMed Author / protein modification

by Molly Chiu, Baylor College of Medicine edited by Lisa Lock, reviewed by Robert Egan Study design overview. Credit: Nature Methods (2025). DOI: 10.1038/s41592-025-02797-x Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and published in Nature Methods, significantly outperforms previously published models and has […]

AI reveals how protein modifications link mutations to disease Read More »

Natural compound could help fight aggressive leukemia and amplify the effect of chemotherapy drugs

August 27, 2025 / Research update / InnovateMed Author / leukemia

by University of Surrey edited by Lisa Lock, reviewed by Andrew Zinin Credit: British Journal of Pharmacology (2025). DOI: 10.1111/bph.70158 Forskolin, a natural compound derived from a plant, could significantly improve treatment outcomes for an aggressive form of leukemia, known as KMT2A-rearranged Acute Myeloid Leukemia (KMT2A-r AML), according to a new study from the University of Surrey. The study, published in the British

Natural compound could help fight aggressive leukemia and amplify the effect of chemotherapy drugs Read More »

Type 1 diabetes in children can be linked to other types of diabetes in parents

August 27, 2025 / Clinical Practice / InnovateMed Author / type 1 diabetes

by Fabienne Landry, McGill University edited by Gaby Clark, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain A recent systematic review and meta-analysis conducted by researchers from the Research Institute of the McGill University Health Center (The Institute) and published in eClinicalMedicine reveals that children of mothers with gestational diabetes or fathers with type 2 diabetes have higher chances

Type 1 diabetes in children can be linked to other types of diabetes in parents Read More »

mRNA vaccine power enhanced for cancer and autoimmune disease prevention

August 27, 2025 / Research update / InnovateMed Author / autoimmune disease

by Yale University edited by Gaby Clark, reviewed by Robert Egan The MVP enhanced the immune response of MPXV mRNA antigens in mice. Credit: Nature Biomedical Engineering (2025). DOI: 10.1038/s41551-025-01478-6 Messenger RNA, or mRNA, vaccines entered the public consciousness when they were introduced during the COVID-19 pandemic, and both Pfizer-BioNTech and Moderna used the technology in developing their highly effective

mRNA vaccine power enhanced for cancer and autoimmune disease prevention Read More »

How cloves might help relieve pain and inflammation

August 27, 2025 / Clinical Practice / InnovateMed Author / clove, inflammation, pain

by Dipa Kamdar, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain Cloves have long been a staple in kitchens and traditional medicine cabinets. Known for their warm, spicy flavor, they’re typically found whole or ground, and as clove oil or extract. But beyond their culinary charm, cloves are gaining scientific attention from researchers and clinicians for

How cloves might help relieve pain and inflammation Read More »

Monthly pill shows potential as pre-exposure prophylaxis HIV drug candidate

August 27, 2025 / Research update / InnovateMed Author / HIV pre-exposure prophylaxis

by Public Library of Science edited by Sadie Harley, reviewed by Robert Egan HIV (yellow) infecting a human immune cell. Credit: Seth Pincus, Elizabeth Fischer and Austin Athman, National Institute of Allergy and Infectious Diseases, National Institutes of Health A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by

Monthly pill shows potential as pre-exposure prophylaxis HIV drug candidate Read More »

Gene variant that protects against cardiovascular diseases hints at safer treatments

August 27, 2025 / Research update / InnovateMed Author / cardiovascular disease

by Ludwig Maximilian University of Munich edited by Gaby Clark, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain Lowering the activity of interleukin-6 (IL-6)—a key immune signal regulating inflammatory responses in the body—could reduce the risk of cardiovascular disease without making people more vulnerable to infections, according to new research from LMU’s Institute for Stroke and Dementia

Gene variant that protects against cardiovascular diseases hints at safer treatments Read More »

Scientists map dendritic cell reactions to mRNA vaccines

August 27, 2025 / Research update / InnovateMed Author / dendritic cell reaction

by VIB (the Flanders Institute for Biotechnology) edited by Gaby Clark, reviewed by Robert Egan Graphical abstract. Credit: Cell Reports (2025). DOI: 10.1016/j.celrep.2025.116150 Belgian scientists have uncovered new details about how the immune system responds to vaccines. Dendritic cells, which are key immune messengers that help kick-start the body’s defenses, show specific responses to lipid nanoparticles. These findings, published in Cell Reports, could

Scientists map dendritic cell reactions to mRNA vaccines Read More »

Benefits of long-term routine lab drug toxicity monitoring unclear in rheumatoid arthritis

August 27, 2025 / Research update / InnovateMed Author / rheumatoid arthriri

by Elana Gotkine edited by Stephanie Baum, reviewed by Andrew Zinin For patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs), long-term routine laboratory toxicity monitoring (lt-RLTM) indicates that most very abnormal laboratory results are already known or suspected, according to a study published online Aug. 26 in the Annals of Internal Medicine. Evy Ulijn, M.D., from Sint Maartenskliniek

Benefits of long-term routine lab drug toxicity monitoring unclear in rheumatoid arthritis Read More »

Mini-organ models reveal hantavirus secrets, point to treatments

August 27, 2025 / Research update / InnovateMed Author / hantavirus, mini organ models

by Tiare Dunlap, University of California, Los Angeles edited by Stephanie Baum, reviewed by Robert Egan Microscopy images of human stem cell-derived mini heart organoids. The left panel shows healthy, beating heart cells, while the right panel shows tissue infected with hantavirus (red), which disrupted cell structure and stopped the organoid’s heartbeat. Credit: Arjit Vijey Jeyachandra /

Mini-organ models reveal hantavirus secrets, point to treatments Read More »