July 30, 2025

AI detects the stiffness of cancer cell exosomes, enhancing lung cancer diagnostic accuracy

by Daegu Gyeongbuk Institute of Science and Technology edited by Sadie Harley, reviewed by Andrew Zinin A schematic diagram of deep learning-based classification technology for extracellular vesicles derived from non-small cell lung cancer (NSCLC) using atomic force microscopy nanomechanical features. Credit: Analytical Chemistry (2025). DOI: 10.1021/acs.analchem.5c02009 A research team has developed a technology that distinguishes lung cancer gene mutations solely […]

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A single artificially sweetened soft drink daily may increase diabetes risk by more than a third

by Monash University edited by Lisa Lock, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain An Australian study has found that drinking just one can of artificially-sweetened soft drink a day may increase the risk of developing type 2 diabetes by 38%. Surprisingly, that risk for artificially sweetened soft drink is even higher than for those who consume sugar-sweetened beverages, such as

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Cholesterol buildup in liver fat droplets directly drives fibrosis in metabolic disease, study finds

by Jordan Shaked, Yale University edited by Lisa Lock, reviewed by Robert Egan Packing defects on the lipid droplet surface under phosphatidylcholine (PC) deficiency compared to phosphatidylethanolamine (PE). Accumulation of free cholesterol on the surface of hepatic lipid droplets under PC deficiency may contribute to the progression of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis

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How the brain shapes what we feel in real time: A new mechanism for modulating sensory signals

by University of Geneva edited by Sadie Harley, reviewed by Robert Egan Cortical neuron expressing green fluorescent protein, imaged in the living mouse brain using two-photon microscopy. Credit: Ronan Chéreau The cerebral cortex processes sensory information via a complex network of neural connections. How are these signals modulated to refine perception? A team from the University of Geneva

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Smart wound monitor poised to improve chronic infection care

by RMIT University edited by Sadie Harley, reviewed by Andrew Zinin Credit: RMIT University Researchers from RMIT University have developed a wearable wound monitoring device with integrated sensors that could reduce infection risks by minimizing the need for frequent physical contact. Their study, “Multiplexed cutaneous wound monitor for point-of-care applications,” was published in Advanced NanoBiomed Research. Standard methods require

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Top 3 Chronic Urticaria Treatments Highlighted in Meta-Analysis

July 24, 2025 In managing antihistamine-refractory chronic urticaria, omalizumab and remibrutinib stand out among the most effective treatments across multiple patient-important outcomes, followed by dupilumab, which shows improvement in urticaria activity, according to a meta-analysis of 42 systemic treatments in 93 studies. All three treatments for chronic urticaria, a condition defined by wheal and itch

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Structure meets function: Glycocalyx analyzed at the molecular level for the first time – imaging

The glycocalyx surrounds each cell in the human body like a coat. This complex sugar layer plays a key role in the progression of numerous diseases, such as cancer and autoimmune diseases. Researchers at the Max Planck Institute for the Science of Light (MPL) have succeeded for the first time in imaging individual sugars within

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Most GLP-1 Prescriptions Miss the Mark: Are Yours?

GLP-1 receptor agonists, including semaglutide, are now widely used for weight loss, offering substantial weight reduction, improved metabolic health, and reduced cardiovascular risk. However, effective treatment involves more than simply prescribing drugs, and ongoing clinical oversight is crucial. Based on recommendations published in JAMA Internal Medicine, the following five tips can help physicians avoid common pitfalls

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‘Mental time travel’ can restore memories to their former state, new study finds

by Krystal Kasal, Phys.org edited by Lisa Lock, reviewed by Robert Egan The rejuvenation hypothesis. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2505120122 Several studies have indicated that forgotten memories may not be as irretrievable as once thought. Memory appears to be closely tied to the context in which it was encoded. Consequently, remembering smells, sounds and

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