June 19, 2025

Unlocking the secrets of gene therapy delivery: New insights into genome ejection from AAV vectors

by The University of Osaka edited by Sadie Harley, reviewed by Robert Egan   Genome ejection and structural changes of viral particles composed of VP1, VP2 and VP3, and the particles composed from VP3 only This figure is a modified version of the graphical abstract from the original paper. Credit: Yuki Yamaguchi A research team at the […]

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Anti-aging drug rapamycin extends life as effectively as restricting calories—new research

by Zahida Sultanova, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin   Molecular pathways involved with dietary restriction, metformin or rapamycin. Arrows imply activation; bars denote inhibition. Figure designed by ZS using BioRender.com. Credit: Aging Cell (2025). DOI: 10.1111/acel.70131 For centuries, humans have searched for ways to extend life. Alchemists never found the philosopher’s stone, but scientists have

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Transformative nutrition: The role of food in an inflammatory skin disease

by Escuela Superior Politecnica del Litoral edited by Sadie Harley, reviewed by Robert Egan   Hidradenitis suppurativa in women. Credit: Evelyn Frias What happens on the skin often begins much deeper. In women living with chronic inflammation, pain, and recurrent skin lesions, the root of the problem may be linked to hormonal, immune, and metabolic imbalances. This is

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Last Signs of Life: What to Expect in Final Hours

Caregivers of terminally ill patients often turn to health professionals to learn what to expect in the final weeks, days, and hours of life. Regardless of the underlying cause, many signs and symptoms are similar during this period. Addressing families’ concerns proactively can ease discomfort and anxiety and help prevent crises that lead to unnecessary ICU admissions.

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Anti-aging “glue” naturally repairs damaged DNA to protect brain cells

By Bronwyn Thompson June 17, 2025 Facebook Twitter Flipboard LinkedIn Reddit Scientists harness a naturally occurring protein to repair aging DNA Created with DALL-E View 2 Images A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including

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Alzheimer’s: Bacteria that cause stomach ulcers may also protect brain

by Gefei Chen, The Conversation edited by Gaby Clark, reviewed by Robert Egan   Physiology, structural organization, and recombinant preparation of H. pylori CagA. Credit: Science Advances (2025). DOI: 10.1126/sciadv.ads7525 Every three seconds, someone in the world develops dementia. Alzheimer’s disease is the most common form of dementia, accounting for between 60% and 70% of all cases. Although scientists have made

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