DNA

Peer-Reviewed PublicationMass General Brigham Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient’s cells. However, most genetic disorders are caused by dozens or even thousands of unique mutations spread across a gene; this diversity results in challenges of scale when it comes to developing customized therapies for many individuals. […]

by Tokyo Metropolitan University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular injection. The team confirmed up to a 14-fold increase in

by Graciela Gutierrez, Baylor College of Medicine edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Retrospective quantification of EBV DNA in the UKB. Credit: Nature (2026). DOI: 10.1038/s41586-025-10020-2 Baylor College of Medicine researchers are part of a collaborative research group with AstraZeneca and Memorial Sloan Kettering Cancer Center that have identified 22

by University of Wisconsin-Madison edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes A model of the human telomerase complex highlights where RPA is predicted to dock. Three structural variants of telomerase that have been linked to patients with various diseases fall within this docking zone, suggesting that these variants could inhibit RPA’s interaction with telomerase. Credit:

by Ecole Polytechnique Federale de Lausanne edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain Our experiences leave traces in the brain, stored in small groups of cells called engrams. Engrams are thought to hold the information of a memory and are reactivated when we remember, which makes them very interesting for research

by University of North Carolina at Chapel Hill edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Visualization of the microscopic “DNA flowers” made by Ronit Freeman in the Freeman Lab at UNC. Credit: Justin Hill, Philip Rosenberg, and Ronit Freeman Researchers at the University of North Carolina have created microscopic soft robots shaped like flowers that

New study takes a deep dive into how TAF1 operates to promote development of new blood cells Peer-Reviewed Publication University of Miami Miller School of Medicine image: A new study led by Stephen D. Nimer, M.D.,director of Sylvester Comprehensive Cancer Center, shows how a key molecule regulates the generation of new blood cells, a process called hematopoiesis that

New molecule halts mitochondrial DNA loss before it triggers inflammation Peer-Reviewed Publication University of California – Riverside image: The developed probe exclusively reacts with mitochondrial DNA repair intermediates and modulates the DNA repair and degradation processes, reducing mitochondrial DNA loss. view moreCredit: Linlin Zhao/UCR When environmental stress harms DNA, it can set off a cascade of failures linked

By Bronwyn Thompson June 17, 2025 Facebook Twitter Flipboard LinkedIn Reddit Scientists harness a naturally occurring protein to repair aging DNA Created with DALL-E View 2 Images A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including