Imagine a living cell as a city. If you were the urban planner for this (very little, very alive) city, one of the things you would have to decide is how to allocate space for different functional uses. Researchers simultaneously visualized six major metabolically active organelles in rainbow yeast cells. Image credit: Mukherji lab […]
A new molecule developed by University at Buffalo researchers acts like a local, long-lasting anesthetic, providing robust pain relief for up to three weeks, according to the results of preclinical studies reported recently in the journal Pain. A new molecule that acts like a local, long-lasting anesthetic that could treat chronic pain like low back
by Gillian Rutherford, University of Alberta edited by Lisa Lock, reviewed by Robert Egan Illustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of Health University of Alberta researchers have created a new tool to help doctors and patients recognize other illnesses commonly associated with inflammatory bowel disease (IBD),
by National University of Singapore edited by Gaby Clark, reviewed by Robert Egan Overview of the NAPTUNE detection process. Probe 1 binds to a specific RNA target, where the enzyme APE1 makes a precise cut, initiating a chain reaction. The resulting DNA fragment activates another enzyme, PfAgo, which then sequentially cuts Probes 2 and 3. Each cutting
by John Tucker, University of Maryland edited by Lisa Lock, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain Until 2023, Adriana Alatorre was in peak condition, running at least 30 miles a week before a mild bout of COVID knocked her off her feet. The 49-year-old Pittsburgh running store manager seemed to recuperate quickly, but after hitting
COVID ‘long-haulers’ lack reliable information, study shows Read More »
by Public Library of Science edited by Sadie Harley, reviewed by Robert Egan Knee braces, water therapy, and exercise are the most beneficial non-drug therapies, per meta-analysis of more than 100 clinical trials involving nearly 10,000 people. Credit: nattanan23, Pixabay, CC0 (creativecommons.org/publicdomain/zero/1.0/) Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee
Simple therapies outperform high-tech options for knee arthritis pain and mobility Read More »
by Johns Hopkins University School of Medicine edited by Lisa Lock, reviewed by Robert Egan The discovery shows that the production of ribosomal RNA (rRNA) is connected to how cells manage RNA splicing (a process that edits RNA). In studies of cancer cell lines using drugs that block rRNA production, a new stress response pathway was revealed.
Blocking a key enzyme could rewire cancer cells and suppress tumor growth Read More »
by Valerie Goodwin, University of Michigan edited by Gaby Clark, reviewed by Robert Egan Working model of impaired tissue recovery after CP in the absence of IL-22BP. IL-22BP is expressed by dendritic cells in peripancreatic lymph nodes under normal conditions. Credit: Cellular and Molecular Gastroenterology and Hepatology (2025). DOI: 10.1016/j.jcmgh.2025.101520 Acute pancreatitis is among the most common gastrointestinal conditions
by Iqbal Pittalwala, University of California – Riverside edited by Stephanie Baum, reviewed by Robert Egan Primary cortical neurons infected with Toxoplasma. Infection with a MOI (multiplicity of infection) of 0.50. For quantifications “n” represents a single cell throughout multiple experiments. (A) Images taken three days post infection. DAPI stains the nucleus, MAP2 stains the perikarya and
How a common brain parasite disrupts neural communication Read More »
by the University of Pennsylvania School of Nursing edited by Stephanie Baum, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain A study published in the Harm Reduction Journal identifies critical factors and strategies for expanding low-barrier wound care services for people who use drugs (PWUD). The research comes at a crucial time, as the rise of xylazine, a tranquilizer found
Expanding essential wound care for people who use drugs Read More »
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