June 17, 2025

Minutes instead of months: Algorithm rapidly identifies cell types to match patients with effective cancer therapies

by Virginia Commonwealth University edited by Robert Egan  Editors’ notes Scientists at VCU have created a new tool called TACIT that could help doctors better understand what is happening inside the body by using advanced computer models to identify different kinds of cells in tissues faster and more accurately than ever before, helping to guide better treatment […]

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Machine learning method helps bring diagnostic testing out of the lab

by Katie Brady, University of Illinois at Urbana-Champaign edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes Credit: Unsplash/CC0 Public Domain What if people could detect cancer and other diseases with the same speed and ease as a pregnancy test or blood glucose meter? Researchers at the Carl R. Woese Institute for Genomic Biology are a step

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Specific immune cells linked to severe organ damage in systemic sclerosis

by The University of Osaka edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Patients with scleroderma renal crisis demonstrated specific enrichment of CD14+ monocytes with increased EGR1 expression and activation of NF-κB–related pathways. Trajectory analysis indicated that they differentiated into macrophages and expressed high levels of THBS1 in the kidney. In patients with SSc-ILD, CD8+ effector

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Blood test can spot early liver transplant issues to prevent organ failure

by Georgetown University Medical Center edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: CC0 Public Domain Liver transplant is a lifesaving surgery, but a significant number of patients experience organ rejection or other complications. Now, a study by scientists from Georgetown University and MedStar Health describes how a single blood sample can be used to

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Early mitochondrial impairment and myelin loss tied to multiple sclerosis brain damage

by University of California – Riverside edited by Robert Egan, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement and balance, potentially leading to tremors, poor coordination,

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Understanding the survivorship experience of older breast cancer patients

by Mass General Brigham edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain The number of older women living with a history of breast cancer in the U.S. is growing, which is due to new diagnoses in patients over 65 and because many women diagnosed at a younger age are living longer. Research

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Tau-PET imaging enables earlier, more accurate Alzheimer’s diagnosis

by University of Gothenburg edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain A brain imaging technology called tau-PET can improve Alzheimer’s diagnostics in health care, according to a study from the University of Gothenburg. The technology enables earlier diagnosis and robustly identifies people at highest risk—even before symptoms appear. Tau-PET is a

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Doctors Could Hack the Nervous System With Ultrasound

A new stimulation technique targets inflammation and diabetes Sangeeta S. Chavan Stavros Zanos 09 Jun 2025 10 min read Shonagh Rae Inflammation: It’s the body’s natural response to injury and infection, but medical science now recognizes it as a double-edged sword. When inflammation becomes chronic, it can contribute to a host of serious health problems, including arthritis, heart

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Eye Complications Found With Use of Semaglutide, Tirzepatide

TOPLINE: At least nine patients using the glucagon-like peptide 1 (GLP-1) receptor agonists semaglutide and tirzepatide developed ophthalmic complications, of whom seven had nonarteritic anterior ischemic optic neuropathy (NAION), according to a case series. Researchers hypothesize that rapid correction of hyperglycemia induced by these drugs may be associated with eye disorders. METHODOLOGY: Researchers reported on

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Novo’s Ozempic Linked to Rare Cases Of Serious Eye Disorder, EU Regulator Says

(Reuters) -Novo Nordisk’s popular weight-loss and diabetes drugs Wegovy and Ozempic may in very rare cases cause a serious eye condition that can lead to vision loss, the European Medicines Agency’s safety committee said on Friday. In the past, studies in type-2 diabetes patients have linked Ozempic to the condition called non-arteritic anterior ischemic optic neuropathy (NAION).

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