June 17, 2025

Ozempic outperforms another diabetes drug for reducing stroke risk

by American College of Physicians edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: Unsplash/CC0 Public Domain Type 2 diabetes patients taking semaglutide, often sold as Ozempic or Wegovy, have a slightly lower risk of stroke compared to patients taking another diabetes drug, empagliflozin. International researchers studied data from 7,899 patients treated with semaglutide and 7,899 […]

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Could a diabetes drug be the key to stopping Alzheimer’s?

By Vijay Kumar Malesu Reviewed by Lauren HardakerJun 17 2025 A new review highlights how diabetes and weight loss drug tirzepatide could disrupt Alzheimer’s disease by repairing brain metabolism and reducing inflammation.  Study: Tirzepatide: a novel therapeutic approach for Alzheimer’s disease. Image credit: Atthapon Raksthaput/Shutterstock.com In a recent review published in the Metabolic Brain Disease, a group of authors

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Can the brain be targeted to treat type 2 diabetes?

Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a study published today in the Journal of Clinical Investigation. For several years, researchers have known that hyperactivity of a subset of neurons located in the hypothalamus, called AgRP neurons, is common in mice

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Fatty liver – but not liver damage – common in type 2 diabetes

Linköping University image: To measure scarring in a patient’s liver with magnet resonance imaging, a vibrator is affixed above the liver. The vibrator causes compression waves in the liver, which can be observed in the images. The more scarring, the faster the wave motion. Credit: Thor Balkhed/Linköping University Six out of ten people with type

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New use for old drug: study finds potential of heart drug for treating growth disorders

Researchers show that phosphodiesterase 3 inhibitors can promote bone growth by stimulating C-type natriuretic peptide signaling Ritsumeikan University image: Researchers have found that phosphodiesterase 3 (PDE3) inhibitors can boost long bone growth. Conventionally used to treat heart disease, thrombosis, and asthma, PDE3 inhibitors can stimulate the C-type natriuretic peptide (CNP) signaling in bone cells, activating

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Gene therapy for glaucoma

PNAS Nexus Gene editing could be used to treat millions of glaucoma patients. Glaucoma is a leading cause of blindness, characterized by high pressure inside the eye. Patients often rely on daily eye drops to lower intraocular pressure, but the drops may cause significant complications, including bradycardia, metabolic acidosis, and kidney stones. In addition, many

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Digital inhalers may detect early warning signs of COPD flare-ups

Digital inhalers can monitor changes in how much air is inhaled, the duration of inhalation COPD Foundation Miami (June 17, 2025) – Digital inhalers may help predict impending acute exacerbations of chronic obstructive pulmonary disease (COPD), according to a new study. The study is published in the May 2025 issue of Chronic Obstructive Pulmonary Diseases: Journal of

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Hollings researcher leads international group suggesting anal cancer screening could cut cancer deaths by up to 65% among high-risk group

Medical University of South Carolina A new paper by a team of scientists from across the U.S. provides quantifiable data that can be used by national groups seeking to create guidelines for anal cancer screening. MUSC Hollings Cancer Center researcher Ashish Deshmukh, Ph.D., co-leader of the Cancer Prevention and Control Research Program at Hollings, is

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New hormonal pathway links oxytocin to insulin secretion in the pancreas

Impact Journals LLC image: Figure 2. Relation of Oxt and glucagon. (A) Representative images of immunostaining for glucagon, insulin and OxtR in an islet (upper panels). Bottom panels are enlarged images of white square in each upper panel. Scale bars in the image indicate 10 μm. (B) The ratio of OxtR intensity in glucagon positive cells and

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Optimal management of erosive esophagitis: An evidence-based and pragmatic approach

Xia & He Publishing Inc. Gastroesophageal reflux disease (GERD) is a prevalent gastrointestinal disorder, with up to 20% of patients developing complications like Erosive esophagitis (EE), Barrett’s esophagus, and esophageal adenocarcinoma. EE, characterized by mucosal necrosis and erosions, presents with symptoms ranging from heartburn to dysphagia and gastrointestinal bleeding. Despite effective pharmacologic treatments, 15% of

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