CKD

Diabetes Management in Chronic Kidney Disease

Latest Guidance Updates November 2022: updates to the sections on top takeaways for clinicians, comprehensive care, glycaemic monitoring and targets, lifestyle interventions, and glucose-lowering therapies. This update includes five updated algorithms, and new sections on sodium–glucose cotransporter-2 inhibitors and mineralocorticoid receptor antagonists. Overview This Medscape guideline summary includes actionable recommendations for the management of type 1 […]

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Chronic kidney disease poisons patients’ hearts, scientists discover

by University of Virginia edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Circulating hCKD-EVs are cardiotoxic in vitro and in vivo. Credit: Circulation (2026). DOI: 10.1161/circulationaha.125.075579 Scientists have discovered an answer to the longstanding mystery of why more than half of patients with chronic kidney disease ultimately die of cardiovascular problems: Their

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What you can do to prevent chronic kidney disease

by Carole Tanzer Miller edited by Andrew Zinin  Editors’ notes  The GIST More than 14% of U.S. adults have some level of chronic kidney disease—and most have no idea. “People with chronic kidney disease generally have no symptoms until they’re very near kidney failure,” said kidney-health researcher Dr. Michael Shlipak of the University of California, San Francisco. Chronic

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Simple method can enable early detection and prevention of chronic kidney disease

by Karolinska Institutet edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Subtle abnormalities in kidney function—even within the range considered normal—may help identify people at risk of developing chronic kidney disease. This is shown in a new study from Karolinska Institutet, published in Kidney International. The researchers

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Updated CKD Management Guideline Focuses on Pharmacotherapy

Nancy A. Melville January 12, 2026 The US Department of Veterans Affairs (VA) and the US Department of Defense (DoD) have issued an updated clinical practice guideline on the management of chronic kidney disease (CKD), focusing on management of early-stage disease at the primary care level. The guideline addresses major recent advances in pharmacologic management, including treatment

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Another critical reason to prevent and control diabetes: It is a top cause of chronic kidney disease

by Sharon Theimer, Mayo Clinic edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: Unsplash/CC0 Public Domain Diabetes affects how the body uses glucose, also known as blood sugar. It can mean that there is too much sugar in the blood. This can harm people in several ways. One serious complication is chronic kidney disease. Ivan Porter II, M.D.,

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Novel Aldosterone Synthase Inhibitor Lorundrostat Shows Promise for Uncontrolled Hypertension in CKD

John Schieszer November 10, 2025 Lorundrostat, a novel aldosterone synthase inhibitor (ASI), added to SGLT2 inhibitors significantly reduced automated office systolic blood pressure (AOSBP) and albuminuria in patients with chronic kidney disease (CKD) and uncontrolled hypertension, the results of a new phase 2 clinical trial showed. “This provides a new opportunity to facilitate blood pressure

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Chronic kidney disease is now the ninth leading cause of death, global analysis finds

by NYU Langone Health edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain Record numbers of men and women globally are now estimated to have reduced kidney function, a new study shows. Figures rose from 378 million people with the disease in 1990 to 788 million in 2023 as the world population grew

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Chronic Kidney Disease: The Blind Spot in Cardiac Care

Daniela Ovadia, MD September 24, 2025   In the daily work of general practice, where every consultation must balance efficiency with accuracy, one parameter is often overlooked yet could transform cardiovascular risk management: the assessment of chronic kidney disease (CKD). At the 25th World Organisation of Family Doctors (WONCA) World Conference 2025, held recently in Lisbon, Portugal, a session

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Lubiprostone May Protect Renal Function in CKD

Edited by Shrabasti Bhattacharya September 03, 2025 TOPLINE: A 16-µg dose of lubiprostone, a medication used in the management of constipation, improved or preserved estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease (CKD), particularly those with moderate disease. The effects likely resulted from stimulating gut bacteria to produce spermidine, which enhanced mitochondrial

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