CKD

TOPLINE: A 16-µg dose of lubiprostone, a medication used in the management of constipation, improved or preserved estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease (CKD), particularly those with moderate disease. The effects likely resulted from stimulating gut bacteria to produce spermidine, which enhanced mitochondrial function and protected the kidneys from further […]

Updates on chronic kidney disease (CKD) diagnosis, use of sodium–glucose cotransporter-2 (SGLT-2) inhibitors as first-line therapy, and personalized treatment approaches for kidney and cardiovascular risk reduction are among the new CKD management recommendations from the Kidney Disease: Improving Global Outcomes (KDIGO) organization. “The last CKD guideline was published in 2012, and there have been so many exciting contributions to