by Paul Hellmich, Technical University Munich Editors’ notes The GIST Add as preferred source A myeloma cell with BCMA (green) on its surface. Credit: Leonie Rieger / TUM Genetically modified immune cells can offer precious additional time to patients with advanced multiple myeloma. However, these therapies lose their impact as the molecules on cancer cells that […]
Established cancer drug can reactivate immunotherapy Read More »
by Rockefeller University edited by Sadie Harley, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients
Cancer drug eliminates aggressive cancers in Phase I trial Read More »
By Lisa O’Mary Old drugs, new ideas. That’s one of the core drivers of using artificial intelligence (AI) for drug development. Researchers using complex AI-fueled methods are now taking aim at what has become a brick wall for precision-focused Alzheimer’s drug development: the complex heterogeneity of both patients and the disease. A new paper in the journal Cell took
Cancer Drugs Could Treat Alzheimer’s: Drug Repurposing Win – Read More »
by University of California, San Francisco edited by Sadie Harley, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain Scientists at UC San Francisco and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its symptoms. The study compared the gene expression signature of
by Agency for Science, Technology and Research (A*STAR), Singapore edited by Sadie Harley, reviewed by Andrew Zinin PRL3 (but not PRL1) is associated with embryonic angiogenesis and blood vessels in PRL3+ tumors have reduced pericyte coverage compared to those in PRL3- tumors. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-59929-2 Singapore researchers have discovered that a new cancer drug, originally developed at A*STAR Institute
Cancer drug shows promise as treatment for blindness Read More »
23 hours ago Philippa Roxby Heath Reporter Laura Marston Laura now feels good six years after her diagnosis of advanced tongue cancer Hundreds of thousands of people with advanced head and neck cancer could live longer without their cancer returning thanks to an immunotherapy drug, a clinical trial suggests. This is the first sign of
Breakthrough cancer drug doubles survival in trial Read More »
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