blood cancer

by Paul Arnold, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain Blood cancer is an umbrella term for a variety of diseases that affect the blood, bone marrow and lymphatic system. Like most cancers, the cause is usually mutations in the DNA, which are genetic errors that accumulate as we

Summary author: Walter Beckwith Peer-Reviewed Publication American Association for the Advancement of Science (AAAS) A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia. The findings offer insight into why some people are naturally more resistant to clonal expansion and age-related

by University of Texas MD Anderson Cancer Center edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain In a recent preclinical study, researchers from The University of Texas MD Anderson Cancer Center developed an antibody therapy called 77A that showed an ability to overcome treatment resistance in blood cancers, such as myeloma and

by Institute of Cancer Research edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: CC0 Public Domain A study carried out by a team of researchers from The Institute of Cancer Research, London, found that combining two types of genetic tests gives doctors a much better chance of identifying multiple myeloma patients who are at risk

by Pasteur Institute edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Observation of cancer cell death in a preclinical model using in vivo two-photon imaging. In magenta, living cancer cells; in blue, dying cancer cells; in green, macrophages. Credit: Dynamics of Immune Responses Unit—Institut Pasteur The aim of immunotherapy strategies is to leverage cells in the

by Naedine Hazell, Yale University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Condensation of CAR on the plasma membrane imaged by TIRF microscopy. CAR is tagged by GFP (cyan). The plasma membrane is labeled by a CellMask deep red dye (magenta). Credit: Nature Chemical Biology (2025). DOI: 10.1038/s41589-025-02031-x Cancer researchers focused on improving the success of cancer

by Albert Einstein College of Medicine edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain A study led by researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) has found that mutations in blood-forming cells may explain the increased risk for leukemia and other blood disorders among first responders exposed

Andrew Artz, MD, MS After years spent caring for older patients with leukemias and other hematologic diseases, Andrew Artz, MD, MS, takes pride in his role of moving the field away from one-size-fits-all approaches. Too many times, he’s seen older adults kept away from the most effective treatments based solely on their age, without thoughtful

by King’s College London edited by Lisa Lock, reviewed by Andrew Zinin Credit: Blood (2025). DOI: 10.1182/blood.2025028560 Researchers from King’s have identified a new way to treat certain blood cancers using existing drugs, by turning a once-dismissed part of our DNA into a therapeutic target. The study, published in Blood, focused on myelodysplastic syndrome (MDS) and chronic lymphocytic leukemia (CLL). These cancers often have mutations in two key genes,