blood cancer

New understanding of how mutations interact could pave way for early detection, prevention strategies by Julia Evangelou Strait•August 21, 2025 DrawImpacts A new WashU Medicine study shows that acquired mutations in blood stem cells — whether arising from smoking, exposure to toxins or even normal aging — interact with mutations passed down by parents in important […]

by University of Montreal edited by Gaby Clark, reviewed by Robert Egan   CD200R1, a CD11b-interacting protein, inhibits phagocytosis. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-60456-3 Immunotherapy has revolutionized cancer treatment by mobilizing the immune system to attack tumor cells. Major advances, such as immune checkpoint inhibitors (notably against the PD-1 protein), have produced impressive results against certain types of cancer,

by FAPESP edited by Stephanie Baum, reviewed by Robert Egan   Credit: Journal of Proteome Research (2025). DOI: 10.1021/acs.jproteome.4c00930 A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer). The CTC is a Research,