Altered cholesterol uptake by neurons in Alzheimer’s disease linked to APOE4 variant

by Sant Pau Research Institute edited by Gaby Clark, reviewed by Andrew Zinin   Astrocyte Cholesterol Efflux to CSF Remains Similar in AD and Control Groups, whereas CSF HDL-like-mediated Cholesterol Delivery to Neurons is Impaired in AD. Credit: Journal of Lipid Research (2025). DOI: 10.1016/j.jlr.2025.100865 A study has identified a key disruption in cholesterol transport to the brain in patients […]

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