New findings suggest symptom patterns may help diagnose Alzheimer’s with FTLD

by Corrie Pikul, Brown University edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: SHVETS production from Pexels People with Alzheimer’s disease often have other neurodegenerative conditions as well, including a less-understood disorder called frontotemporal lobar degeneration (FTLD). While a precise diagnosis of FTLD has only been possible during an […]

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Largest-ever Parkinson’s study shows how symptoms differ between men and women

by Lyndsey Collins-Praino, The Conversation edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Parkinson’s disease is the fastest growing neurological disorder, with more than 10 million cases worldwide. Up to 150,000 Australians currently live with the disease and 50 new cases are diagnosed each day. The number of people living

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The hidden signals of Crohn’s disease: Why remission is not recovery

by Yael Haberman edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Summary of the incomplete recovery of gut signals during Crohn’s disease remission. Credit: Gastroenterology (2026). DOI: 10.1053/j.gastro.2025.12.007 Imagine a patient with Crohn’s disease—after months of flares, they are finally in clinical remission. Their biomarkers are stable, their pain has subsided,

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The Alzheimer’s gut-brain link: How butyrate could curb amyloid-β buildup and inflammation

by Ingrid Fadelli, Medical Xpress edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source A) Immunoblot profile of synthetic Aβ preparation containing monomers, dimers, trimers, tetramers and high molecular weight oligomers. B) IF staining of HuC/D, Tuj1 (green) and Aβ (red) in Ctrl and Aβ-treated pure enteric neurons isolated from WT

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Shingles vaccine drastically cuts risk of serious cardiac events

by American College of Cardiology edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: www.kaboompics.com from Pexels People with heart disease who received a shingles vaccine had nearly half the rate of serious cardiac events a year later compared with those who did not get the vaccine, according to a

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No evidence to suggest medicinal cannabis is effective for depression, anxiety or PTSD, says systematic review

by University of Sydney edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain A landmark paper published in Lancet Psychiatry—the largest-ever review of the safety and efficacy of cannabinoids across a range of mental health conditions—found no evidence that medicinal cannabis is effective in treating anxiety, depression or

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Smart bandage could heal and monitor wounds at the same time

by Cherry Cai, RMIT University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source The smart wound patch’s dual function could support more timely and effective intervention from clinicians. Credit: RMIT University Researchers have unlocked the possibility of creating smart wound dressings that enable real-time monitoring while also being able to

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Three anesthesia drugs all have the same effect in the brain, researchers find

by Massachusetts Institute of Technology edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain When patients undergo general anesthesia, doctors can choose among several drugs. Although each of these drugs acts on neurons in different ways, they all lead to the same result: a disruption of the

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A theory of Alzheimer’s disease linking amyloid beta and tau

by PNAS Nexus edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Amyloid beta and tau proteins compete for the same binding sites on microtubules in neurons, suggesting that displacement of tau by amyloid beta, rather than aggregation of either protein, may be the primary driver of

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Can science slow down aging? Q&A with geneticist

by Olivia Maule, Stanford University edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Geneticist Anne Brunet explores what aging really is, how lifestyle choices might influence longevity, and the promising frontiers of aging research. Aging is a process that affects us all. But how many of

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