February 5, 2026

Fatty acids found to influence immune defense during chronic infections

by Mario Aguilera, University of California – San Diego edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Our immune system employs an array of strategies to combat infectious threats. White blood cells called cytotoxic T lymphocytes, or “CD8 T cells,” are soldiers of the immune system, […]

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Five mutational ‘fingerprints’ could help predict how visible tumors are to the immune system

by HUN-REN Szegedi Biológiai Kutatóközpont edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Original illustration showing how exposure-linked mutation patterns may influence tumor immune visibility, supporting the idea that immunotherapy response depends on mutation ‘fingerprints’ and their protein-level consequences, not mutation counts alone.” Credit: Máté Manczinger, HUN-REN Szeged Biological

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Experimental pill dramatically reduces ‘bad’ cholesterol

by UT Southwestern Medical Center edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: JESHOOTS.com from Pexels An experimental pill called enlicitide slashed levels of low-density lipoprotein (LDL) cholesterol, commonly known as “bad” cholesterol, by up to 60%, according to a new phase three clinical trial published in the New England Journal of Medicine.

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Blocking PTP1B protein may slow memory loss in Alzheimer’s

by Gina DiPietro, Cold Spring Harbor Laboratory edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source The Tonks lab studied PTP1B inhibition in a mouse model of Alzheimer’s disease. When PTP1B was deleted, as shown in the bottom row, the brain’s immune cells (green) were better at engulfing harmful amyloid-β plaques

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Turning around the Titanic’: How the incoming PBM reforms will transform CMS

February 3, 2026 02:34 PM ESTUpdated 04:31 PM PharmaLaw ‘Turning around the Titanic’: How the incoming PBM reforms will transform CMS Zachary Brennan Senior Editor The Centers for Medicare and Medicaid Services has never played a significant role in regulating pharmacy benefit managers, the middlemen that have historically relied on high drug prices for profits.

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What if multiple sclerosis isn’t just one disease?

By Chelsea Haney February 04, 2026 Facebook Twitter LinkedIn Reddit Flipboard Email The findings indicate MS could have two distinct degenerative pathways, one fast and the other slow. And this knowledge could help better inform patients and doctors. Depositphotos View 1 Images For decades, multiple sclerosis (MS) has been defined primarily by its symptoms, rather than

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New stem cell treatment may offer hope for Parkinson’s disease

Keck Medicine of USC investigates a unique therapy that aims to repair damaged brain cells Reports and ProceedingsUniversity of Southern California – Health Sciences image: Brian Lee, MD, PhD, is a neurosurgeon with Keck Medicine of USC and principal investigator of the study. view more  Credit: Ricardo Carrasco III LOS ANGELES — Parkinson’s disease is a progressive neurodegenerative disorder that affects more

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New approach to HIV treatment offers hope to reduce daily drug needs

Enhanced immune cells show promise in targeting viral reservoirs that current medications can’t eliminate Peer-Reviewed PublicationCase Western Reserve University image: Jonathan Karn view more  Credit: Case Western Reserve University CLEVELAND— More than 30 million people with HIV must take antiretroviral therapy (ART) medications daily to keep the virus under control, according to the Joint United Nations Programme

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Rates of autism in girls and boys may be more equal than previously thought

by British Medical Journal edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Autism has long been viewed as a condition that predominantly affects male individuals, but a study from Sweden published by The BMJ shows that autism may actually occur at comparable rates among male and female individuals.

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