February 2, 2026

Artificial Intelligence on Trial: Who’s Liable When Clinical Algorithms Go Wrong?

Margaret Lozovatsky, MD, FAMIA, has spent years helping health systems adopt digital tools designed to improve patient care. As a pediatric hospitalist, she has also seen what can go wrong. In one case, a predictive artificial intelligence (AI) model flagged a healthy infant as having an 89% mortality risk — not because the child was […]

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Rethinking longevity: Genes account for 50% of human lifespan variation, study suggests

by Weizmann Institute of Science edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Extrinsic mortality masks life-span correlations in twin cohorts.(A) Human mortality rates after age 15 show an early plateau driven by extrinsic mortality such as accidents or infections, followed by an exponential increase described by the Gompertz law,

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Alternate path for inflammation could improve rheumatoid arthritis treatment

by Shawn Vestal, Washington State University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Towfiqu barbhuiya from Pexels The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don’t work for up to 4 of every 10 patients. New research

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Secondhand vape plumes could form lung-damaging radicals

by American Chemical Society edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Electronic cigarettes—or vapes—can release puffs of vapor in aromatic clouds. The health risks of breathing in this secondhand or passive vapor aren’t fully understood. So, researchers reporting in Environmental Science & Technology conducted a preliminary study on lingering

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A benchmark for antibodies: Open dataset aims to standardize sequencing and measurement

by University of Oslo edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Figure illustrating the study. The upper layer introduces the knowledge gap in antibody sequencing. The middle layer provides a brief overview of the experiment where the researchers put antibody mixtures in LC/MS-MS and tried to reconstruct the sequences

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Specialized sensor tracks wound pH continuously to monitor healing

by Koc University edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Detailed illustration of the layer-by-layer layout of the patch with a schematic representation of its working principle. Credit: ACS Sensors (2025). DOI: 10.1021/acssensors.4c02172 In a study led by Assoc. Prof. Dr. Levent Beker from the Department of Mechanical Engineering at Koç

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A new molecular atlas of tau enables precision diagnostics and drug targeting across neurodegenerative diseases

by Children’s Hospital Boston edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Graphical abstract. Credit: Cell (2026). DOI: 10.1016/j.cell.2025.12.036 Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as “tauopathies”). New research led by Boston Children’s Hospital challenges the current “one-size-fits-all” approach to diagnosing and treating these tauopathies.

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Engineered micro scaffolds show promise for helping people recover from severe muscle loss

by Rachel Bedford, University of Oregon edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Myoblasts attaching to the MEW scaffolds. Blue shows the muscle cell nucleus (DAPI), and pink shows the filaments of the muscle cells (F-actin). Here, you can see the grid design of the scaffold that the cells

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Stimulating the brain with electromagnetic therapy after stroke may help reduce disability

by American Heart Association edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source The brain has about 100 billion cells called neurons. It’s made up of distinct parts, that developed through human evolution. Credit: American Heart Association A type of therapy that stimulates specific brain pathways with electromagnetic pulses combined with

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Gut-derived metabolite hippuric acid ‘turns up’ immune inflammation, study finds

by The Wistar Institute edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Graphical abstract. Credit: Cell Reports (2026). DOI: 10.1016/j.celrep.2025.116749 Scientists at The Wistar Institute have identified a previously overlooked mediator in the body’s response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea,

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