antibodies

A benchmark for antibodies: Open dataset aims to standardize sequencing and measurement

by University of Oslo edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Figure illustrating the study. The upper layer introduces the knowledge gap in antibody sequencing. The middle layer provides a brief overview of the experiment where the researchers put antibody mixtures in LC/MS-MS and tried to reconstruct the sequences […]

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Antibodies targeting IgE Cε2 domain show promise for rapid allergy relief

by Juntendo University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Researchers identify antibody fragments capable of removing immunoglobulin E bound to mast cells, revealing a potentially fast-acting therapy for severe allergic diseases. Credit: Tomoaki Ando of Juntendo University Allergic diseases represent a major global health burden, placing significant strain

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New antibodies developed that can inhibit inflammation in autoimmune diseases

Two first-in-class antibodies were developed that specifically block the high-affinity IgG receptor FcγRI Peer-Reviewed Publication University Medical Center Utrecht image: Prof. Jeanette Leusen, PhD (left) and colleagues at the Center for Translational Immunology (UMC Utrecht) view more   Credit: Ed van Rijswijk An international research group directed by UMC Utrecht have developed and characterized two first-in-class antibodies

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Scientists shed light on origins of common peanut antibodies in humans

by Massachusetts General Hospital edited by Sadie Harley, reviewed by Robert Egan   Credit: Pixabay/CC0 Public Domain Why do people develop antibodies to food? While clinicians have long observed that healthy humans develop a particular type of antibody, called IgG, to the foods they eat, the reasons for this phenomenon have remained unknown. Researchers, led by investigators from

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