January 20, 2026

Inflammatory pathway reveals targetable weakness in hard-to-treat blood cancer

by Indiana University edited by Robert Egan  Editors’ notes  The GIST Add as preferred source Kate Ho is working in the lab. Credit: Indiana University New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia by identifying the blood cancer’s reliance on a specific signaling pathway involved in the […]

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Scientists design artificial pain receptor that senses pain intensity and self-heals

by Sanjukta Mondal, Phys.org edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Biological and artificial nociceptive nerves with the capability of pain rating. Credit: Advanced Functional Materials, 2025. DOI: https://doi.org/10.1002/adfm.202528900 All over the body are tiny sensors called nociceptors whose job is to spot potentially harmful stimuli and send warning

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58% of patients affected by 2022 mpox outbreak report lasting physical symptoms

by American College of Physicians edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain A cohort study of over 300 adults either diagnosed with mpox between May 2022 to January 2023 (post-MPX) or who were at risk but never infected (no-MPX) found that more than half of

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Being cold doesn’t make you sick, so why are illnesses more common in winter?

by Manal Mohammed, The Conversation edited by Gaby Clark, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Andrea Piacquadio from Pexels Many people across cultures grow up hearing that cold weather makes you sick. Going outside without a coat, breathing in cold air, sleeping in a chilly room, getting caught in cold rain

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AI model detects prediabetes using ECG data without need for blood tests

by Institute of Science Tokyo edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Institute of Science Tokyo DiaCardia, a novel artificial intelligence model that can accurately identify individuals with prediabetes using either 12-lead or single-lead electrocardiogram (ECG) data, has been developed. This breakthrough holds promise for future home-based prediabetes

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Machine learning can predict patients’ responses to antidepressants—while disentangling drug and placebo effects

by Ingrid Fadelli, Medical Xpress edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Characterization of structure-function covariation predicting antidepressant and placebo responses. Credit: Nature Mental Health (2025), DOI: 10.1038/s44220-025-00541-0 Depression is one of the most widespread mental health disorders worldwide, affecting approximately 4% of the global population. It is characterized by a

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No short cuts—but a bit of sugar—in the quest to fight cancer relapse

by Jeff Kelley, Virginia Commonwealth University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Virginia Commonwealth University Medical researchers typically play the long game, spending years (and years and years) exploring an idea that could move beyond the laboratory to improve human life. At Virginia Commonwealth University, Umesh Desai,

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Unusual KRAS mutation in pancreatic cancer may explain less aggressive tumors

by Medical University of South Carolina edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source A new study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, sheds light on why pancreatic tumors with the KRAS G12R mutation behave differently from other KRAS-driven cancers and why

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Pediatricians offer advice on dealing with warts

by Carolena Steinberg and Diana H. Lee edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Warts are small, firm bumps on the skin caused by viruses from the human papillomavirus (HPV) family. Warts are common among school-aged children but can affect people of any age.

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Most elderly cancer patients receive inappropriate drugs until final months, study finds

by University of Tsukuba edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain Analysis of the medical records of 1,269 elderly patients with advanced cancer by researchers at the University of Tsukuba has found that more than 70% were prescribed potentially inappropriate medications (PIMs) and that the

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