January 16, 2026

How beige fat keeps blood pressure in check

by Rockefeller University edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source A mouse aorta with immunofluorescent tagging, emphasizing the close connection between vasculature and fat. Credit: Weslie R. and William H. Janeway Laboratory of Molecular Metabolism at The Rockefeller University Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease […]

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Altered microbiome: Oral bacteria play a role in chronic liver disease, study reveals

by Technical University Munich edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Experimental validation of prtC gene. Credit: Nature Microbiology (2025). DOI: 10.1038/s41564-025-02223-0 Each year, more than two million people die from advanced chronic liver disease (ACLD). Previous research has linked gut microbiome disruptions to this condition and suggested that bacteria typically

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Dormant cancer cells can change shape to survive immune system attack

by Ian Demsky, Memorial Sloan Kettering Cancer Center edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Dormant lung cancer cells change their shape from spindle-shaped (above) to round (below), which helps protect them from the body’s immune defenders. Credit: Wang, Z., et al., Nature Cancer (CC BY 4.0) Cancer cells

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Why a life-threatening sedative is being prescribed more often for seniors

by Rutgers University edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain When agitated dementia patients wander or shout through the night, families and caregivers understandably feel the need to treat this frightening and potentially dangerous behavior. Antipsychotic medications are often resorted to with such patients, contributing

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Novel theranostic model shows curative potential for gastric and pancreatic tumors

by Rebecca Maxey, Society of Nuclear Medicine and Molecular Imaging edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Evaluation of [89Zr]Zr-DFO-zolbetuximab PET specificity in mouse models of GCa over multiple time points. (A and B) Maximum-intensity-projection serial PET/CT images for male nude mice implanted with GSU gastric tumors (white

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Sudden cardiac arrest in athletes: Hidden heart conditions can trigger rare but fatal events during competition

by Avi Patel, Yale University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Rachel Lampert, MD, with a patient. Credit: Yale University Though rare, sudden cardiac arrest (SCA) in athletes often unfolds in high-visibility settings, like sports arenas, prompting questions about underlying causes, emergency preparedness, and long-term outcomes. A new

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What a study of 67,000 people reveals about sexual desire and age

by Paul Arnold, Medical Xpress edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Sexual desire is a fundamental part of being human and a driving force in many relationships, yet we still don’t fully understand why it varies so much from person to person. In a

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Q&A: Why is flu so bad this year?

by Ryan Hughes, University of South Florida edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain Flu levels are elevated and continuing to rise during the 2026 season, with Influenza A emerging as the dominant strain. People across the country, including in the Tampa Bay area, are

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Cardiovascular risk factors in childhood linked to adult cognitive function

by Elana Gotkine edited by Stephanie Baum, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Cardiovascular risk factors, including higher body mass index (BMI) and waist circumference, in childhood and adolescence are associated with poorer cognitive function in young adulthood, according to a study published online Jan. 15 in Pediatrics. Henri Salo, M.D., from the University

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New ALS treatment target identified: STAUFEN-1 protein reduction protects brain cells from death

by University of Utah edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source RNA-seq revealed a transcriptional signature of inhibition of apoptosis and immune responses by STAU1 KD in HEK293 cells. A Volcano plot with highlighted DEGs. B Modified gene sets identified by GSEA-Hallmark pathway analysis. C Top 10 IPA canonical pathways ranked by p-value. D IPA canonical pathways with

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