December 22, 2025

Huntington’s disease: Could a cancer drug hold the key?

How the drug may work Combining with other drugs Medication used to treat cancer could potentially be an effective therapy for Huntington’s disease. The drug may also offer a pathway to treat other neurodegenerative diseases. In 2017, Dr. Albert La Spada, director of the Duke Center for Neurodegeneration and Neurotherapeutics, published research with colleagues from […]

Huntington’s disease: Could a cancer drug hold the key? Read More »

From a small town in Wales, a scientific sleuth has shaken Dana-Farber — and elevated the issue of research integrity

By Andrew Joseph Jan. 27, 2024 Sholto David has flagged issues on more than 2,000 papers on a site called PubPeer, where researchers critique published scientific studies.Francesca Jones for STAT Reprints PONTYPRIDD, Wales — The blog post that has shaken the leadership of Boston’s Dana-Farber Cancer Institute, one of the world’s preeminent cancer research centers, was

From a small town in Wales, a scientific sleuth has shaken Dana-Farber — and elevated the issue of research integrity Read More »

When is surgery necessary for gout, and what are the options?

Is surgery necessary? Options How to decide Aftercare Surgery and gout flares Gout’s effects on the body Flare treatment Summary Surgery may help reduce pain and other symptoms of severe gout. The three main types of surgery for more advanced gout include tophi removal, joint fusion, and joint replacement. Gout is a chronic, inflammatory form

When is surgery necessary for gout, and what are the options? Read More »

Chrononutrition Explained: Why When You Eat Matters for Metabolic Health

By Pooja Toshniwal PahariaReviewed by Benedette Cuffari, M.Sc. Introduction An overview of the circadian rhythm Why nighttime eating matters Best foods to eat at night Foods to limit or avoid in the evening Effects on cardiometabolic health Practical guidelines References Further reading Late-night meals can quietly derail glucose control and cardiovascular health. Here’s what chrononutrition research and

Chrononutrition Explained: Why When You Eat Matters for Metabolic Health Read More »

Researchers Uncover a Backup Defense System in the Gut

The immune system in our gut encounters a surge of foreign substances every day, whether it’s the food we consume or the microbes that find their way in. To keep things in check, specialized antibodies—known as immunoglobulin A (IgA)—form a protective mucosal barrier in the gut that traps and neutralizes pathogens, preventing them from sticking

Researchers Uncover a Backup Defense System in the Gut Read More »

A urine-based biological aging clock: Machine learning and microRNA offer accurate prediction

by Justin Jackson, Medical Xpress edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain Craif Inc. in Nagoya, Japan, working with Nagoya University’s Institute of Innovation for Future Society, has developed a urine-based biological aging clock. In validation of the method, predicted ages came within 4.4 years of chronological age on average. Aging,

A urine-based biological aging clock: Machine learning and microRNA offer accurate prediction Read More »

Cutting carbs, not fat, may better control appetite in women

By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Lauren HardakerDec 19 2025 A short-term clinical trial suggests that cutting carbohydrates, not fat, may be better for curbing food cues and emotional eating in women living with lipedema. Study: Hedonic hunger and eating behavior after low-carbohydrate versus low-fat diets in females with lipedema and obesity. Image credit: sweet marshmallow/Shutterstock.com A

Cutting carbs, not fat, may better control appetite in women Read More »

A new strategy for immune tolerance

Peer-Reviewed Publication Nano Life Science Institute (NanoLSI), Kanazawa University image: Engineered antigen-presenting extracellular vesicles (AP-EVs) deliver peptide-MHCII, IL-2, and TGF-β to naïve antigen-specific CD4⁺ T cells, driving their differentiation into Foxp3⁺ regulatory T cells (Tregs). The induced Tregs suppress autoreactive T cells and modulate surrounding immune cells to promote antigen-specific immune tolerance. view more  Credit: ©

A new strategy for immune tolerance Read More »

Open-source software sheds light on cancer’s hidden genetic networks

by Universidad de Navarra edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes From left to right: The authors of the study, José González, Rubén Armañanzas, and Aitor Oviedo. Credit: Manuel Castells University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene regulation networks with applications in cancer survival analysis. The

Open-source software sheds light on cancer’s hidden genetic networks Read More »

Scroll to Top