immune tolerance

by Salk Institute edited by Alexander Pol  Editors’ notes  The GIST Add as preferred source Corn is one of the three foods, alongside soybean and wheat, that contained a protein Jamie Blum, Ph.D., discovered helps regulate oral tolerance. Credit: Salk Institute In little moments like when sipping coffee or licking an ice cream cone, it doesn’t seem […]

by Kanazawa University edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Engineered antigen-presenting extracellular vesicles (AP-EVs) deliver peptide-MHCII, IL-2, and TGF-β to naïve antigen-specific CD4⁺ T cells, driving their differentiation into Foxp3⁺ regulatory T cells (Tregs). The induced Tregs suppress autoreactive T cells and modulate surrounding immune cells to promote antigen-specific immune tolerance. Credit: Drug Delivery (2025). DOI:

Peer-Reviewed Publication Nano Life Science Institute (NanoLSI), Kanazawa University image: Engineered antigen-presenting extracellular vesicles (AP-EVs) deliver peptide-MHCII, IL-2, and TGF-β to naïve antigen-specific CD4⁺ T cells, driving their differentiation into Foxp3⁺ regulatory T cells (Tregs). The induced Tregs suppress autoreactive T cells and modulate surrounding immune cells to promote antigen-specific immune tolerance. view more  Credit: ©